KIAA0101 Protein (His tag)
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- 抗原 See all KIAA0101 (PAF) 蛋白
- KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This KIAA0101 protein is labelled with His tag.
- 原理
- Recombinant Human KIAA0101/p15/PAF Protein (His Tag)
- 序列
- Met 1-Glu 111
- 产品特性
- A DNA sequence encoding the human PAF isoform 1 (NP_055551.1) (Met 1-Glu 111) was expressed, with a polyhistide tag at the N-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PAF 蛋白
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PCNA Clamp Associated Factor (PAF) (AA 1-111) protein (His tag)
PAF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
PCNA Clamp Associated Factor (PAF) (AA 1-111) protein (GST tag)PAF 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
PCNA Clamp Associated Factor (PAF) (AA 1-111) protein (Strep Tag)Crystallography grade PAF 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
PCNA Clamp Associated Factor (PAF) (AA 1-110) protein (Strep Tag)Crystallography grade PAF 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
PCNA Clamp Associated Factor (PAF) (AA 1-111), (full length) protein (GST tag)PAF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
PCNA Clamp Associated Factor (PAF) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PAF 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))
- 别名
- KIAA0101/p15/PAF (PAF 产品)
- 别名
- NS5ATP9 Protein, OEATC Protein, OEATC-1 Protein, OEATC1 Protein, PAF Protein, PAF15 Protein, p15(PAF) Protein, p15/PAF Protein, p15PAF Protein, paf Protein, Paf Protein, AA409629 Protein, Ns5apt9 Protein, Ns5atp9 Protein, mKIAA0101 Protein, Kiaa0101 Protein, PCNA clamp associated factor Protein, PCNA clamp associated factor S homeolog Protein, PCLAF Protein, pclaf Protein, pclaf.S Protein, Pclaf Protein
- 背景
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Background: KIAA0101, also known as p15(PAF), is a proliferating cell nuclear antigen-associated factor which interacts with proliferating cell nuclear antigen(PCNA). It was initially isolated in a yeast two-hybrid screen for PCNA binding partners, and was shown to bind PCNA competitively with the cell cycle regulator p21(WAF). KIAA0101 is localized primarily in the nucleus. It shares the conserved PCNA binding motif with several other PCNA binding proteins including CDK inhibitor p21 . KIAA0101 is involved in cell proliferation and plays a role in early tumor recurrence (ETR), and prognosis of hepatocellular carcinoma (HCC). KIAA0101 is expressed predominantly in liver, pancreas and placenta. It cannot be detected in heart or brain. It is highly expressed in a number of tumors, especially esophageal tumors, in anaplastic thyroid carcinomas and in non-small-cell lung cancer lines. Overexpression of KIAA0101 predicts high stage, early tumor recurrence, and poor prognosis of hepatocellular carcinoma. It also may be involved in protection of cells from UV-induced cell death.
Synonym: KIAA0101,L5,NS5ATP9,OEATC,OEATC-1,OEATC1,p15(PAF),p15/PAF,p15PAF,PAF,PAF15
- 分子量
- 13.8 kDa
- NCBI登录号
- NP_055551
- 途径
- Chromatin Binding
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