NPM1 Protein (His tag)
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- 抗原 See all NPM1 蛋白
- NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This NPM1 protein is labelled with His tag.
- 原理
- Recombinant Human NPM1/Nucleophosmin Protein (His Tag)
- 序列
- Met 9-Leu 158
- 产品特性
- A DNA sequence encoding the human NPM1 isoform 1 (P06748-1) N-terminal segment (Met 9-Leu 158) was expressed, with a polyhistide tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
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Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 1-294) protein (GST tag)
NPM1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 1-294) protein (His tag)NPM1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (AA 1-292) protein (His tag)NPM1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) proteinNPM1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NPM1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NPM1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 6.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
- 别名
- NPM1/Nucleophosmin (NPM1 产品)
- 别名
- B23 Protein, NPM Protein, NO38 Protein, Npm Protein, B23NP Protein, npm4 Protein, npm Protein, CG7917 Protein, CRP1 Protein, Crp1 Protein, Dmel\\CG7917 Protein, dNLP Protein, dNLP-S Protein, p22 Protein, npm1 Protein, sb:cb487 Protein, nucleophosmin 1 Protein, nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog Protein, nucleophosmin 1b Protein, Nucleophosmin Protein, nucleophosmin Protein, nucleophosmin (nucleolar phosphoprotein B23, numatrin) Protein, Nucleoplasmin Protein, nucleophosmin 1a Protein, NPM1 Protein, Npm1 Protein, npm1.L Protein, npm1b Protein, npm Protein, Nlp Protein, npm1a Protein
- 背景
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Background: Nucleophosmin 1 (NPM1), also known as nucleolar phosphoprotein B23 or numatrin, is a member of the nucleoplasmin family. Nucleophosmin (NPM) is a nucleolar phosphoprotein that plays multiple roles in ribosome assembly and transport, cytoplasmic-nuclear trafficking, centrosome duplication and regulation of p53. The NPM1 gene is frequently involved in chromosomal translocation, mutation and deletion. Mutations of the NPM1 gene leading to the expression of a cytoplasmic mutant protein, NPMc+, are the most frequent genetic abnormalities found in acute myeloid leukemias. Acute myeloid leukemias (AML) with mutated NPM1 have distinct characteristics, including a significant association with a normal karyotype, involvement of different hematopoietic lineages, a specific gene-expression profile and clinically, a better response to induction therapy and a favorable prognosis. In addition, NPM1 is a crucial gene to consider in the context of the genetics and biology of cancer. NPM1 is frequently overexpressed, mutated, rearranged and deleted in human cancer. Traditionally regarded as a tumour marker and a putative proto-oncogene, it has now also been attributed with tumour-suppressor functions.
Synonym: B23,NPM
- 分子量
- 17.8 kDa
- 途径
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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