NCF1 Protein (His tag)
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- 抗原 See all NCF1 蛋白
- NCF1 (Neutrophil Cytosol Factor 1 (NCF1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This NCF1 protein is labelled with His tag.
- 原理
- Recombinant Human Neutrophil Cytosol Factor 1/NCF1 Protein (His Tag)
- 序列
- Met 1-Val390
- 产品特性
- Recombinant Human Neutrophil cytosol factor 1 is produced by our E.coli expression system and the target gene encoding Met1-Val390 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NCF1 蛋白
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Neutrophil Cytosol Factor 1 (NCF1) (AA 1-390) protein (Strep Tag)
Crystallography grade NCF1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Neutrophil Cytosol Factor 1 (NCF1) protein (Myc-DYKDDDDK Tag)NCF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris 100 mM NaCl,1 mM DTT, pH 8.0.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NCF1 (Neutrophil Cytosol Factor 1 (NCF1))
- 别名
- Neutrophil Cytosol Factor 1/NCF1 (NCF1 产品)
- 别名
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NCF1A Protein, NOXO2 Protein, SH3PXD1A Protein, p47phox Protein, Ncf-1 Protein, p47
Protein, neutrophil cytosolic factor 1 Protein, NCF1 Protein, Ncf1 Protein - 背景
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Background: Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a membrane bound cytochrome b558 are required for the activation of the latent NADPH oxidase. The human NCF1 gene encodes a 390 amino acids protein without a signal peptide. The NCF1 gene interacts with other subunits of nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) and plays an important role in innate immunity, producing reactive oxygen species and reducing the severity and duration of parasitic infection and autoimmune disease. NCF1 also has a role in T cell activation.
Synonym: NCF-1,47 kDa autosomal chronic granulomatous disease protein/47 kDa neutrophil oxidase factor,NCF-47K,Neutrophil NADPH oxidase factor 1,Nox organizer 2,Nox-organizing protein 2/SH3 and PX domain-containing protein 1A,p47-phox
- 分子量
- 45.6 kDa
- UniProt
- P14598
- 途径
- PI3K-Akt Signaling
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