NETO1 Protein (His tag)
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- 抗原 See all NETO1 蛋白
- NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NETO1 protein is labelled with His tag.
- 原理
- Recombinant Human NETO1/BTCL1 Protein (His Tag)
- 序列
- Met 1-Thr 344
- 产品特性
- A DNA sequence encoding the human NETO1 isoform 3 (NP_620416.1) extracellular domain (Met 1-Thr 344) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NETO1 蛋白
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Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 1-533) protein (GST tag)
NETO1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 434-533) protein (GST tag)NETO1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 23-344) protein (His tag)Crystallography grade NETO1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 366-533) protein (His tag)Crystallography grade NETO1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 366-533) protein (His tag)Crystallography grade NETO1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 23-344) protein (His tag)Crystallography grade NETO1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 23-533) protein (rho-1D4 tag)Crystallography grade NETO1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1) (AA 23-533) protein (rho-1D4 tag)Crystallography grade NETO1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))
- 别名
- NETO1/BTCL1 (NETO1 产品)
- 别名
- BCTL1 Protein, BTCL1 Protein, AI851453 Protein, Btcl1 Protein, C130005O10Rik Protein, RGD1566269 Protein, neuropilin and tolloid like 1 Protein, neuropilin (NRP) and tolloid (TLL)-like 1 Protein, NETO1 Protein, Neto1 Protein
- 背景
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Background: Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus representing a novel subfamily of CUB- and LDLa-containing proteins. The cytoplasmic domains of NETO1 and NETO2 are not homologous to other known protein sequences but contain a conserved FXNPXY-like motif, which is essential for the internalization of clathrin coated pits during endocytosis or alternatively, may be implicated in intracellular signaling pathways. NETO1 and NETO2, have marked effects on receptor properties, increasing further the potential diversity of Kainate receptors (KARs) functional properties. NETO1 involves in the development and/or maintenance of neuronal circuitry. NETO1 regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
Synonym: BCTL1,BTCL1
- 分子量
- 38 kDa
- NCBI登录号
- NP_620416
- 途径
- Regulation of long-term Neuronal Synaptic Plasticity
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