NEGR1 Protein (His tag)
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- 抗原 See all NEGR1 蛋白
- NEGR1 (Neuronal Growth Regulator 1 (NEGR1))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This NEGR1 protein is labelled with His tag.
- 原理
- Recombinant Mouse NEGR1 Protein (His Tag)
- 序列
- Met 1-Gly 318
- 产品特性
- A DNA sequence encoding the mouse NEGR1 (NP_001034183.1) (Met 1-Gly 318) without the pro peptide was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 94 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product NEGR1 蛋白
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Neuronal Growth Regulator 1 (NEGR1) (AA 228-327) protein (GST tag)
NEGR1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Neuronal Growth Regulator 1 (NEGR1) (AA 38-324) protein (His tag)Crystallography grade NEGR1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Neuronal Growth Regulator 1 (NEGR1) (AA 32-318) protein (His tag)Crystallography grade NEGR1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NEGR1 (Neuronal Growth Regulator 1 (NEGR1))
- 别名
- NEGR1 (NEGR1 产品)
- 别名
- zgc:100871 Protein, NEGR1 Protein, Ntra Protein, kilon Protein, DMML2433 Protein, IGLON4 Protein, KILON Protein, 5330422G01Rik Protein, mKIAA3001 Protein, NTRA-L Protein, NTRA-S Protein, neuronal growth regulator 1 Protein, neuronal growth regulator 1 L homeolog Protein, negr1 Protein, NEGR1 Protein, negr1.L Protein, Negr1 Protein
- 背景
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Background: Neuronal Growth Regulator 1, NEGR1, also known as neurotractin, or KILON, which belongs to the immunoglobulin superfamily, IgLON family. This GPI-linked cell surface glycoprotein NEGR1 is composed of three Ig-like domains and belongs to the IgLON subgroup of neural IgSF members. It is expressed in two isoforms with apparent molecular masses of 50 and 37 kD, termed L-form and S-form, respectively. NEGR1/Neurotractin participates in the regulation of neurite outgrowth in the developing brain, and is expressed on neurites of primary hippocampal neurons. Neurotractin/KILON is a trans-neural growth-promoting factor for outgrowing axons following hippocampal denervation. KILON (kindred of IgLON) and opioid-binding cell adhesion molecule belong to the IgLON subgroup of immunoglobulin superfamily together with the limbic system-associated membrane protein and neurotrimin. The alteration of modulatory function of KILON/NEGR1 for the number of dendritic synapses concomitant with changes in its localization and detergent solubility during neuronal culture development. In addition to its reported role in the brain, NEGR1 is also expressed in subcutaneous adipose tissue and acts as a central 'hub' in an obesity-related transcript network.
Synonym: 5330422G01Rik,KILON,Ntra
- 分子量
- 33 kDa
- NCBI登录号
- NP_001034183
- 途径
- Feeding Behaviour
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