Neurexin 3 Protein (NRXN3) (Fc Tag)
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- 抗原 See all Neurexin 3 (NRXN3) 蛋白
- Neurexin 3 (NRXN3)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Neurexin 3 protein is labelled with Fc Tag.
- 原理
- Recombinant Human NRXN3 Protein (Fc Tag)(Active)
- 序列
- Met 1-Thr 357
- 产品特性
- A DNA sequence encoding the human NRXN3 isoform 2 (NP_620426.2) extracellular domain (Met 1-Thr 357) was fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. When 5 x 10E4 cells/well are added to NRXN3 coated plates (0.8 μg/ml and 100 μl/well), >30 % will adhere specifically after 60 minutes at 37°C.
- Top Product
- Discover our top product NRXN3 蛋白
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Neurexin 3 (NRXN3) (AA 101-210) protein (GST tag)
NRXN3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Neurexin 3 (NRXN3)
- 别名
- NRXN3 (NRXN3 产品)
- 别名
- C14orf60 Protein, NRXN3 Protein, NRXNIII Protein, im:7144250 Protein, nrxn3aa Protein, nrxn3ab Protein, wu:fj54c11 Protein, neurexin 3 Protein, neurexin III Protein, neurexin-3 Protein, neurexin 3a Protein, neurexin 3b Protein, NRXN3 Protein, Nrxn3 Protein, nrxn3 Protein, LOC490812 Protein, nrxn3a Protein, nrxn3b Protein
- 背景
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Background: Neurexin-3-beta; also known as Neurexin III-beta and NRXN3; is a single-pass type I membrane protein which belongs to the neurexin family. It contains one laminin G-like domain. It is a neuronal cell surface protein that may be involved in cell recognition and cell adhesion. Neurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of which two; NRXN1 and NRXN3; are among the largest known human genes. Three of the genes ( NRXN1; NRXN2; NRXN3 ) utilize two alternate promoters and include numerous alternatively spliced exons to generate thousands of distinct mRNA transcripts and protein isoforms. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms; a much smaller number of transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. The alpha-neurexins contain EGF-like sequences and laminin G domains; and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. NRXN3 have been linked to genetic predisposition towards a number of conditions such as alcohol or drug addiction; or obesity.
Synonym: C14orf60
- 分子量
- 61.6 kDa
- NCBI登录号
- NP_620426
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