NCKIPSD Protein (GST tag)
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- 抗原 See all NCKIPSD 蛋白
- NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This NCKIPSD protein is labelled with GST tag.
- 原理
- Recombinant Human NCKIPSD/SPIN90 Protein (GST Tag)
- 序列
- Met 1-Thr 244
- 产品特性
- A DNA sequence encoding the mature form of human NCKIPSD (Q9NZQ3-3) (Met1-Thr244) was expressed with the GST tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product NCKIPSD 蛋白
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NCK Interacting Protein with SH3 Domain (NCKIPSD) (AA 1-99) protein (GST tag)
NCKIPSD 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
NCK Interacting Protein with SH3 Domain (NCKIPSD) (AA 1-715) protein (GST tag)NCKIPSD 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
NCK Interacting Protein with SH3 Domain (NCKIPSD) (AA 1-722) protein (Strep Tag)Crystallography grade NCKIPSD 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
NCK Interacting Protein with SH3 Domain (NCKIPSD) (AA 1-714) protein (Strep Tag)Crystallography grade NCKIPSD 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
NCK Interacting Protein with SH3 Domain (NCKIPSD) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NCKIPSD 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))
- 别名
- NCKIPSD/SPIN90 (NCKIPSD 产品)
- 别名
- AF3P21 Protein, DIP Protein, DIP1 Protein, ORF1 Protein, SPIN90 Protein, VIP54 Protein, WASLBP Protein, WISH Protein, Wasbp Protein, SH3 adapter protein SPIN90 Protein, NCK interacting protein with SH3 domain Protein, CpipJ_CPIJ019280 Protein, NCKIPSD Protein, Nckipsd Protein
- 背景
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Background: NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. NCKIPSD also plays an important role in stress fiber formation. NCKIPSD gene is involved in therapy-related leukemia by a chromosomal translocation t(3,11)(p21,q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified. NCKIPSD is a SH3 domain protein. Fas ligand is a cytotoxic effector molecule of T and NK cells which is characterized by an intracellular N-terminal polyproline region that serves as a docking site for SH3 and WW domain proteins. Several previously described Fas ligand-interacting SH3 domain proteins turned out to be crucial for the regulation of storage, expression and function of the death factor. Recent observations, however, indicate that Fas ligand is also subject to posttranslational modifications including shedding and intramembrane proteolysis.
Synonym: AF3P21,DIP,DIP1,ORF1,SPIN90,VIP54,WASLBP,WISH
- 分子量
- 53.2 kDa
- 途径
- Protein targeting to Nucleus
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