B7-H6 Protein (His tag)
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- 抗原 See all B7-H6 (NCR3LG1) 蛋白
- B7-H6 (NCR3LG1) (Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This B7-H6 protein is labelled with His tag.
- 原理
- Recombinant Human B7-H6 Protein (His Tag)(Active)
- 序列
- Met 1-Ser262
- 产品特性
- A DNA sequence encoding the human NCR3LG1 (NP_001189368.1) (Met1-Ser262) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized human B7-H6 -His at 10μg/mL (100μL/well) can bind human NCR3-Fch, the EC50 of human NCR3-Fch is 6-200ng/mL.
- Top Product
- Discover our top product NCR3LG1 蛋白
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Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) protein (Fc Tag)
NCR3LG1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) protein (His tag)NCR3LG1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-259) protein (His tag)NCR3LG1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) protein (His-Avi Tag,Biotin)NCR3LG1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) (Active) protein (His tag)NCR3LG1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) (Active) protein (Fc Tag,AVI tag,Biotin)NCR3LG1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) (Active) protein (His tag,AVI tag,Biotin)NCR3LG1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by reduced SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- B7-H6 (NCR3LG1) (Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1))
- 别名
- B7-H6 (NCR3LG1 产品)
- 别名
- B7-H6 Protein, B7H6 Protein, DKFZp686O24166 Protein, natural killer cell cytotoxicity receptor 3 ligand 1 Protein, NCR3LG1 Protein
- 背景
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Background: Natural cytotoxicity triggering receptor 3 ligand 1(B7-H6) is a glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H6 consists of a 238 amino acid (aa) extracellular domain (ECD) that contains one Ig-like V domain and one Ig-like C1 domain, a 21 aa transmembrane segment, and a 171 aa cytoplasmic domain that contains one ITIM, one SH2, and one SH3 motif. Both of the Ig-like domains carry N-linked glycosylation. The Ig-like V domain mediates 1:1 stoichiometric binding of B7-H6 to NKp30 expressed on NK cells. It does not show binding to NKp44, NKp46, or NKG2D. Ligation of NKp30 by B7-H6 induces NK cell activation and target cell cytolysis. B7-H6 is expressed on a wide range of hematopoietic, carcinoma, and melanoma tumor cells, which is consistent with the detection of NKp30 binding sites on many tumors.
Synonym: B7-H6,B7H6,DKFZp686O24166
- 分子量
- 28.1 kDa
- NCBI登录号
- NP_001189368
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