NKp44/NCR2 Protein (His tag)
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- 抗原 See all NKp44/NCR2 (NCR2) 蛋白
- NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NKp44/NCR2 protein is labelled with His tag.
- 原理
- Recombinant Human NCR2/NKp44/CD336 Protein (His Tag)
- 序列
- Met 1-Pro 190
- 产品特性
- A DNA sequence encoding the human NCR2 (NP_004819.2) extracellular domain (Met 1-Pro 190) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 88 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NCR2 蛋白
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Natural Cytotoxicity Triggering Receptor 2 (NCR2) (AA 22-192) protein (His tag)
Crystallography grade NCR2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Natural Cytotoxicity Triggering Receptor 2 (NCR2) (AA 22-276) protein (rho-1D4 tag)Crystallography grade NCR2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Natural Cytotoxicity Triggering Receptor 2 (NCR2) (AA 19-130) protein (His tag)NCR2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % by SDS - PAGE SDS
Natural Cytotoxicity Triggering Receptor 2 (NCR2) protein (Myc-DYKDDDDK Tag)NCR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))
- 别名
- NCR2/NKp44/CD336 (NCR2 产品)
- 别名
- CD336 Protein, LY95 Protein, NK-p44 Protein, NKP44 Protein, dJ149M18.1 Protein, uncharacterized LOC609023 Protein, natural cytotoxicity triggering receptor 2 Protein, LOC609023 Protein, NCR2 Protein
- 背景
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Background: Natural cytotoxicity triggering receptor 2 (NCR2), also known as Natural killer cell p44-related protein (NKp44), or CD336, is a member of the natural cytotoxicity receptor (NCR) family, which composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. It is a novel transmembrane glycoprotein belonging to the Immunoglobulin superfamily characterized by a single extracellular V-type domain. The cytoplasmic domain of NKp44 also contains a sequence that matches the immunoreceptor tyrosine-based inhibitory motif (ITIM) consensus. This Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp44 is selectively expressed by IL-2-activated NK cells and may contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis. Tumor cell recognition of the mutated NKp44 proteins was significantly reduced and correlated with their lower recognition of heparin.
Synonym: CD336,dJ149M18.1,LY95,NK-p44,NKP44,RP1-149M18.2
- 分子量
- 20 kDa
- NCBI登录号
- NP_004819
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