NAALADL1 Protein (His tag)
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- 抗原 See all NAALADL1 蛋白
- NAALADL1 (N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NAALADL1 protein is labelled with His tag.
- 原理
- Recombinant Human NAALADL1 Protein (His Tag)
- 序列
- Pro 29-Leu 740
- 产品特性
- A DNA sequence encoding the extracellular domain of human NAALADL1 (NP_005459.2) (Pro 29-Leu 740) was expressed, with a polyhistidine tag at the N-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- Discover our top product NAALADL1 蛋白
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N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1) protein (His tag)
NAALADL1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1) protein (Myc-DYKDDDDK Tag)NAALADL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NAALADL1 (N-Acetylated alpha-Linked Acidic Dipeptidase-Like 1 (NAALADL1))
- 别名
- NAALADL1 (NAALADL1 产品)
- 别名
- I100 Protein, NAALADASEL Protein, Gm964 Protein, Naaladasel Protein, N-acetylated alpha-linked acidic dipeptidase like 1 Protein, N-acetylated alpha-linked acidic dipeptidase-like 1 Protein, NAALADL1 Protein, Naaladl1 Protein
- 背景
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Background: N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidylpeptidase, is a Single-pass type I I membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. NAALADase L is a chloride-activated, membrane bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.
Synonym: I100,NAALADASEL,NAALADL1
- 分子量
- 80 kDa
- NCBI登录号
- NP_005459
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