MAP4K2 Protein (GST tag,His tag)
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- 抗原 See all MAP4K2 蛋白
- MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This MAP4K2 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human MAP4K2/GC Kinase Protein (His & GST Tag)
- 序列
- Met 1-Tyr 812
- 产品特性
- A DNA sequence encoding the human MAP4K2 (AAH47865.1) (Met 1-Tyr 812) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 87 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MAP4K2 蛋白
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Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (AA 1-820) (Active) protein (GST tag)
MAP4K2 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (AA 1-820) protein (GST tag)MAP4K2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (AA 1-820) protein (Strep Tag)Crystallography grade MAP4K2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) (AA 1-821) protein (Strep Tag)Crystallography grade MAP4K2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) protein (Myc-DYKDDDDK Tag)MAP4K2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 50 mM Tris, 100 mM NaCl, pH 8.0
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
- 别名
- MAP4K2/GC Kinase (MAP4K2 产品)
- 别名
- BL44 Protein, GCK Protein, RAB8IP Protein, AI385662 Protein, Rab8ip Protein, MAP4K2 Protein, dZ150L22.2 Protein, map4k2l Protein, map4k2l-2 Protein, map4k3l Protein, si:dz150l22.2 Protein, si:dz263j20.1 Protein, zgc:136670 Protein, mitogen-activated protein kinase kinase kinase kinase 2 Protein, mitogen activated protein kinase kinase kinase kinase 2 Protein, MAP4K2 Protein, Map4k2 Protein, LOC103346779 Protein, map4k2 Protein
- 背景
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Background: Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein and MAP4K2, is a cytoplasm and peripheral membrane protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. MAP4K2 contains one CNH domain and one protein kinase domain. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. MAP4K2 can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. It is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1 / MEKK1. MAP4K2 enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. It may also play a role in the regulation of vesicle targeting or fusion.
Synonym: BL44;GCK;MAP4K2;RAB8IP
- 分子量
- 119 kDa
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