MVK Protein (GST tag,His tag)
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- 抗原 See all MVK 蛋白
- MVK (Mevalonate Kinase (MVK))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This MVK protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human MVK/Mevalonate kinase Protein (His & GST Tag)
- 序列
- Met 1-Leu 396
- 产品特性
- A DNA sequence encoding the human MVK (Q03426) (Met1-Leu396) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- Discover our top product MVK 蛋白
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Mevalonate Kinase (MVK) protein (His tag)
MVK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Mevalonate Kinase (MVK) (AA 1-396) protein (GST tag)MVK 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Mevalonate Kinase (MVK) (AA 297-396) protein (GST tag)MVK 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Mevalonate Kinase (MVK) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)MVK 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Mevalonate Kinase (MVK) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)MVK 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, 2 mM DTT, pH 7.4, 10 % glycerol
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- MVK (Mevalonate Kinase (MVK))
- 别名
- MVK/Mevalonate kinase (MVK 产品)
- 别名
- F21A20.160 Protein, F21A20_160 Protein, MEVALONATE KINASE Protein, MVK Protein, mevalonate kinase Protein, DDBDRAFT_0168621 Protein, DDBDRAFT_0302479 Protein, DDB_0168621 Protein, DDB_0302479 Protein, LRBP Protein, MK Protein, MVLK Protein, POROK3 Protein, 2310010A05Rik Protein, AI256848 Protein, AI414037 Protein, zgc:103473 Protein, mevalonate kinase Protein, mvk Protein, hypothetical protein Protein, MVK Protein, MK Protein, MA_RS03165 Protein, PAB_RS02890 Protein, LMOf2365_0011 Protein, mvk Protein, RCI_RS14145 Protein, TGAM_RS08735 Protein, MMAH_RS07705 Protein, TAGG_RS01605 Protein, SHELL_RS02965 Protein, MVOL_RS03085 Protein, Igag_1464 Protein, VDIS_RS11260 Protein, MFER_RS04560 Protein, DESMU_RS01555 Protein, ARCVE_RS02955 Protein, MZHIL_RS05110 Protein, Mvk Protein
- 背景
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Background: Mevalonate kinase belongs to the GHMP kinase family, Mevalonate kinase subfamily. It can be found in a wide variety of organisms from bacteria to mammals. Mevalonate kinase may be a regulatory site in cholesterol biosynthetic pathway. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy, and ataxia. Defects in mevalonate kinase can also cause hyperimmunoglobulinemia D and periodic fever syndrome (HIDS). HIDS is an autosomal recessive disease characterized by recurrent episodes of unexplained high fever associated with skin rash, diarrhea, adenopathy (swollen, tender lymph nodes), athralgias and/or arthritis.
Synonym: LRBP,MK,MVLK,POROK3
- 分子量
- 70.2 kDa
- UniProt
- Q03426
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