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MCEE Protein (His tag)

MCEE 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318778
发货至: 中国
  • 抗原 See all MCEE 蛋白
    MCEE (Methylmalonyl CoA Epimerase (MCEE))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 2
    • 2
    • 1
    资源
    • 5
    • 1
    • 1
    • 1
    人细胞
    标记
    This MCEE protein is labelled with His tag.
    原理
    Recombinant Human MCEE Protein (His Tag)
    序列
    Gln37-Ala176
    产品特性
    Recombinant Human Methylmalonyl-CoA epimerase is produced by our Mammalian expression system and the target gene encoding Gln37-Ala176 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product MCEE 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM DTT,10 % Glycerol, pH 7.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    MCEE (Methylmalonyl CoA Epimerase (MCEE))
    别名
    MCEE (MCEE 产品)
    别名
    MGC89112 Protein, zgc:112343 Protein, MGC116480 Protein, GLOD2 Protein, 1110007A04Rik Protein, methylmalonyl-CoA epimerase Protein, methylmalonyl CoA epimerase Protein, methylmalonyl-CoA epimerase S homeolog Protein, MCEE Protein, mcee Protein, mcee.S Protein, Mcee Protein
    背景

    Background: Methylmalonyl-CoA epimerase, mitochondrial(MCEE)is an enzyme which belongs to the glyoxalase I family. It converts (S)-methylmalonyl-CoA to the (R) form, catalyses the following chemical reaction: (R)-methylmalonyl-CoA (S)-methylmalonyl-CoA. It plays an important role in the catabolism of fatty acids with odd-length carbon chains. This protein deficiency is an autosomal recessive inborn error of AA metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduria can appear in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties, pancytopenia and coma.

    Synonym: Methylmalonyl-CoA epimerase, mitochondrial,DL-methylmalonyl-CoA racemase

    分子量
    16.0 kDa
    UniProt
    Q96PE7
    途径
    Monocarboxylic Acid Catabolic Process
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