MTSS1 Protein (AA 1-250) (His tag,MBP tag)
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- 抗原 See all MTSS1 蛋白
- MTSS1 (Metastasis Suppressor 1 (MTSS1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-250
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This MTSS1 protein is labelled with His tag,MBP tag.
- 原理
- Recombinant Human MTSS1 Protein (aa1-250, His & MBP Tag)
- 序列
- Met 1-Ser 250
- 产品特性
- A DNA sequence encoding the human MTSS1 (EAW92073.1) N-terminal fragment (Met 1-Ser 250) was fused with an N-terminal polyhistidine-tagged MBP tag at the N-terminus.
- 纯度
- > 80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MTSS1 蛋白
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Metastasis Suppressor 1 (MTSS1) (AA 346-445) protein (GST tag)
MTSS1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- MTSS1 (Metastasis Suppressor 1 (MTSS1))
- 别名
- MTSS1 (MTSS1 产品)
- 别名
- MTSS1 Protein, MIM Protein, MIMA Protein, MIMB Protein, 2310003N14Rik Protein, BC024131 Protein, D130001D01Rik Protein, Mim Protein, mKIAA0429 Protein, mim Protein, mima Protein, mimb Protein, mtss1 Protein, MTSS1, I-BAR domain containing Protein, transmembrane protein 65 Protein, metastasis suppressor protein 1 Protein, metastasis suppressor 1 Protein, metastasis suppressor 1, gene 2 L homeolog Protein, MTSS1 Protein, TMEM65 Protein, LOC100547471 Protein, mtss1 Protein, Mtss1 Protein, mtss1.2.L Protein
- 背景
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Background: MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expressed in a variety of tissues. MTSS1 might be involved in shaping neuronal membranes in vivo. MTSS1 deforms phosphoinositide-rich membranes through its I-BAR domain and interacts with actin monomers through its WH2 domain. MTSS1/MIM was first identified as a metastasis suppressor missing in metastatic bladder carcinoma cell lines. MTSS1 is a prognostic indicator of disease-free survival in breast cancer patients and demonstrates the ability to play a role in governing the metastatic nature of breast cancer cells. MTSS1 may serve as a useful biomarker for the prediction of outcome of gastric cancer. The down-regulation of MTSS1 that may be caused by DNA methylation was also observed in many other types of cancer.Recent work proposed that MIM also potentiates Sonic hedgehog (Shh)-induced gene expression. MTSS1 as a multiple functional molecular player and has an important role in development, carcinogenesis and metastasis.
Synonym: MIM,MIMA,MIMB
- 分子量
- 71.8 kDa
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