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MESDC2 Protein (His tag)

MESDC2 宿主: 人 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317713
发货至: 中国
  • 抗原 See all MESDC2 蛋白
    MESDC2 (Mesoderm Development Candidate 2 (MESDC2))
    蛋白类型
    Recombinant
    宿主
    • 2
    • 1
    • 1
    • 1
    资源
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This MESDC2 protein is labelled with His tag.
    原理
    Recombinant Human MESDC2/MESD Protein (His Tag)
    序列
    Ala 34-Lys 230
    产品特性
    A DNA sequence encoding the human MESDC2 (NP_055969.1) (Ala 34-Lys 230) was fused with a signal peptide at the N-terminus and a polyhistidine tag at the C-terminus.
    纯度
    > 97 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product MESDC2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    MESDC2 (Mesoderm Development Candidate 2 (MESDC2))
    别名
    MESDC2/MESD (MESDC2 产品)
    别名
    MGC115616 Protein, MESDC2 Protein, BOCA Protein, MESD Protein, 2210015O11Rik Protein, AW537813 Protein, mKIAA0081 Protein, mesd Protein, msd Protein, zgc:158636 Protein, mesoderm development LRP chaperone Protein, mesoderm development LRP chaperone L homeolog Protein, mesoderm development candidate 2 Protein, MESD Protein, mesd.L Protein, CpipJ_CPIJ010816 Protein, Tsp_04045 Protein, mesd Protein, Mesd Protein, MESDC2 Protein
    背景

    Background: LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61 and MESDC2, is a member of the MESD family. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for specification of embryonic polarity and mesoderm induction.

    Synonym: BOCA,MESD

    分子量
    23.6 kDa
    NCBI登录号
    NP_055969
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