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MDGA2 Protein (His tag)

MDGA2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
产品编号 ABIN7196922
发货至: 中国
  • 抗原 See all MDGA2 蛋白
    MDGA2 (MAM Domain Containing Glycosylphosphatidylinositol Anchor 2 (MDGA2))
    蛋白类型
    Recombinant
    宿主
    • 1
    • 1
    • 1
    小鼠
    资源
    • 2
    • 1
    HEK-293 Cells
    标记
    This MDGA2 protein is labelled with His tag.
    原理
    Recombinant Mouse MDGA2/MAMDC1 Protein (His Tag)
    序列
    Met 1-Asp 924
    产品特性
    A DNA sequence encoding the mouse MDGA2 isoform 1 (P60755-1) without the propeptide (Met 1-Asp 924) was expressed, fused with a polyhistidine tag at the C-terminus.
    纯度
    > 90 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    MDGA2 (MAM Domain Containing Glycosylphosphatidylinositol Anchor 2 (MDGA2))
    别名
    MDGA2/MAMDC1 (MDGA2 产品)
    别名
    MAMDC1 Protein, c14_5286 Protein, 6720489L24Rik Protein, 9330209L04Rik Protein, Adp Protein, Mamdc1 Protein, MAM domain containing glycosylphosphatidylinositol anchor 2 Protein, MDGA2 Protein, Mdga2 Protein
    背景

    Background: MAM domain-containing glycosylphosphatidylinositol anchor protein 2, also known as MAM domain-containing protein 1, MDGA2 and MAMDC1, is a cell membrane protein which contains six Ig-like (immunoglobulin-like) domains and one MAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single MAM domain. Biochemical characterization demonstrates that MDGA1 and MDGA2 proteins are highly glycosylated, and that MDGA1 is tethered to the cell membrane by a GPI anchor. The MDGAs are differentially expressed by subpopulations of neurons in both the central and peripheral nervous systems, including neurons of the basilar pons, inferior olive, cerebellum, cerebral cortex, olfactory bulb, spinal cord, and dorsal root and trigeminal ganglia. The similarity of MDGAs to other Ig-containing molecules and their temporal-spatial patterns of expression within restricted neuronal populations, for example migrating pontine neurons and D1 spinal interneurons, suggest a role for these novel proteins in regulating neuronal migration, as well as other aspects of neural development, including axon guidance.

    Synonym: 6720489L24Rik;9330209L04Rik;Adp;Mamdc1

    分子量
    103 kDa
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