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LY86 Protein (His tag)

LY86 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE
产品编号 ABIN7320457
发货至: 中国
  • 抗原 See all LY86 蛋白
    LY86 (Lymphocyte Antigen 86 (LY86))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 1
    • 1
    小鼠
    资源
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This LY86 protein is labelled with His tag.
    原理
    Recombinant Mouse MD1 Protein (His Tag)
    序列
    Met 1-Ser 162
    产品特性
    A DNA sequence encoding the extracellular domain (Met 1-Ser 162) of mouse LY86 (NP_034875.1) precursor was expressed with a C-terminal polyhistidine tag.
    纯度
    > 92 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product LY86 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    LY86 (Lymphocyte Antigen 86 (LY86))
    别名
    MD1 (LY86 产品)
    别名
    MD-1 Protein, MMD-1 Protein, dJ80N2.1 Protein, MD1 Protein, LY86 Protein, lymphocyte antigen 86 Protein, LY86 Protein, Ly86 Protein
    背景

    Background: MD-1 and MD-2 are secretory glycoproteins that exist on the cell surface in complexes with transmembrane proteins. MD-1 is anchored by radioprotective 105 (RP105) which is a molecule containing leucine-rich repeats and is expressed on B cells, dentritic cells and macrophages, while MD-2 is associated with TLR4. MD-1 is required for efficient RP105 cell surface expression and function. It is indicated that the RP105/MD1 complex, in conjunction with TLR4, mediates the innate immune response to LPS in B cells, and also plays a role in protecting against apoptosis, B-cell proliferation, etc. Mouse MD-1 cDNA encodes a 162 amino acid precursor protein with a putative 19 aa signal peptide and two potential N-linked glycosylation sites. It shares 40 % and 66 % amino acid sequence identity with chicken and human MD-1 respectively. MD-1 is mainly expressed in spleen, and also detectable in liver, brain, thymus, and kidney.

    Synonym: MD-1,MD1

    分子量
    18 kDa
    NCBI登录号
    NP_034875
    途径
    Toll-Like Receptors Cascades
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