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Galectin 9 Protein (His tag)

LGALS9 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7318515
发货至: 中国
  • 抗原 See all Galectin 9 (LGALS9) 蛋白
    Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 17
    • 5
    • 4
    • 3
    • 2
    • 2
    资源
    • 20
    • 6
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This Galectin 9 protein is labelled with His tag.
    原理
    Recombinant Human Galectin 9/LGALS9 Protein (His Tag)(Active)
    序列
    Met 1-Thr323
    产品特性
    Recombinant Human Galectin 9 is produced by our Mammalian expression system and the target gene encoding Met1-Thr323 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human Galectin 9-His at 10μg/ml(100 μl/well) can bind Cynomolgus TIM-3-His(Cat: PKSQ050023). The ED50 of Human Galectin 9-His is 1.75 ug/ml .
    Top Product
    Discover our top product LGALS9 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS,5 % Trehalose,1 mM EDTA, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))
    别名
    Galectin 9/LGALS9 (LGALS9 产品)
    别名
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    背景

    Background: Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.

    Synonym: Galectin-9, Gal-9, Ecalectin, Tumor Antigen HOM-HD-21, LGALS9

    分子量
    36.9 kDa
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