JTB Protein (Fc Tag)
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- 抗原 See all JTB 蛋白
- JTB (Jumping Translocation Breakpoint (JTB))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This JTB protein is labelled with Fc Tag.
- 原理
- Recombinant Human Jumping Translocation Breakpoint/JTB Protein (Fc Tag)
- 序列
- Met 1-Leu105
- 产品特性
- A DNA sequence encoding the human JTB (O76095-1) (Met1-Leu105) was fused with Fc region of mouse IgG at the C-terminus.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product JTB 蛋白
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Jumping Translocation Breakpoint (JTB) (AA 31-105) protein (His tag)
JTB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Jumping Translocation Breakpoint (JTB) (AA 1-146) protein (GST tag)JTB 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Jumping Translocation Breakpoint (JTB) (AA 31-146) protein (rho-1D4 tag)Crystallography grade JTB 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Jumping Translocation Breakpoint (JTB) (AA 31-146) protein (rho-1D4 tag)Crystallography grade JTB 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- JTB (Jumping Translocation Breakpoint (JTB))
- 别名
- Jumping Translocation Breakpoint/JTB (JTB 产品)
- 别名
- HJTB Protein, HSPC222 Protein, PAR Protein, hJT Protein, Gm622 Protein, JTB Protein, jumping translocation breakpoint Protein, JTB Protein, Jtb Protein
- 背景
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Background: Jumping translocation breakpoint, also known as JTB, is a member of the JTB family. Jumping translocation (JT) is an unbalanced translocation that comprises amplified chromosomalsegments jumping to various telomeres. JTB is expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts. It is required for normal cytokinesis during mitosis. JTB plays a role in the regulation of cell proliferation. It may be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.
Synonym: hJT,HJTB,HSPC222,JTB,PAR
- 分子量
- 34.7 kDa
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