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IL-7 Protein (His tag)

IL7 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
产品编号 ABIN7320603
发货至: 中国
  • 抗原 See all IL-7 (IL7) 蛋白
    IL-7 (IL7) (Interleukin 7 (IL7))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 27
    • 12
    • 5
    • 1
    • 1
    • 1
    • 1
    小鼠
    资源
    • 19
    • 13
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This IL-7 protein is labelled with His tag.
    原理
    Recombinant Mouse Interleukin-7/IL-7 Protein (His Tag)(Active)
    序列
    Glu26-Ile154
    产品特性
    Recombinant Mouse Interleukin-7 is produced by our Mammalian expression system and the target gene encoding Glu26-Ile154 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 25-160 pg/ml.
    Top Product
    Discover our top product IL7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL-7 (IL7) (Interleukin 7 (IL7))
    别名
    Interleukin-7/IL-7 (IL7 产品)
    别名
    IL7 Protein, IL-7 Protein, A630026I06Rik Protein, Il-7 Protein, hlb368 Protein, interleukin 7 Protein, IL7 Protein, Il7 Protein
    背景

    Background: Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88 % aa sequence identity with rat IL-7 and 58-60 % with human, equine, bovine, ovine, porcine, feline and canine IL-7. It is widely expressed in primary and secondary lymphoid tissues cell and stromal epithelial cells of the thymus, bone marrow, and intestines. IL-7 activation of IL-7 R alpha is critical for both T cell and B cell lineage development. It is important for proliferation during certain stages of B-cell maturation. IL-7 contributes to the maintenance of all na?ve and memory T cells, mainly by promoting expression of the anti-apoptotic protein Bcl-2. It is required for optimal T cell-dendritic cell interaction.

    Synonym: IL-7, IL-7 interleukin-7, interleukin-7, Lymphopoietin -1, PBGF

    分子量
    15.9 kDa
    UniProt
    P10168
    途径
    JAK/STAT Signaling
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