IL5RA Protein (His tag)
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- 抗原 See all IL5RA 蛋白
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- Baculovirus infected Insect Cells
- 标记
- This IL5RA protein is labelled with His tag.
- 原理
- Recombinant Mouse IL-5RA/IL-5 Rα Protein (Baculovirus, His Tag) (Active)
- 序列
- Met1-Val328
- 产品特性
- A DNA sequence encoding the mouse IL5Ra (P21183) (Met1-Val328) was expressed with a C-terminal polyhistidine tag.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- 1.Measured by its binding ability in a functional ELISA. 2.Immobilized mouse IL5Ra-His at 10μg/mL (100μL/well) can bind biotinylated mouse IL5-His, the EC50 of biotinylated mouse IL5-His is 30-100ng/mL.
- Top Product
- Discover our top product IL5RA 蛋白
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Interleukin 5 Receptor, alpha (IL5RA) (AA 21-335) protein (His-Avi Tag,Biotin)
IL5RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 Receptor, alpha (IL5RA) (AA 18-339) protein (His tag)IL5RA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 Receptor, alpha (IL5RA) (AA 21-335) protein (Fc Tag)IL5RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 Receptor, alpha (IL5RA) (AA 21-335) protein (His-Avi Tag)IL5RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 Receptor, alpha (IL5RA) (Active) protein (His tag)IL5RA 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 5 Receptor, alpha (IL5RA) protein (His tag)IL5RA 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 5 Receptor, alpha (IL5RA) (AA 21-342) protein (His tag)Crystallography grade IL5RA 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 5 Receptor, alpha (IL5RA) (AA 18-339) protein (His tag)Crystallography grade IL5RA 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 5 Receptor, alpha (IL5RA) (AA 21-420) protein (rho-1D4 tag)Crystallography grade IL5RA 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 5 Receptor, alpha (IL5RA) (AA 18-415) protein (rho-1D4 tag)Crystallography grade IL5RA 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
- 别名
- IL-5RA/IL-5 Ralpha (IL5RA 产品)
- 别名
- MGC86517 Protein, IL5RA Protein, il5r Protein, cdw125 Protein, hsil5r3 Protein, gpIL-5ra Protein, CD125 Protein, CDw125 Protein, HSIL5R3 Protein, IL5R Protein, Il5r Protein, interleukin 5 receptor subunit alpha L homeolog Protein, interleukin 5 receptor subunit alpha Protein, interleukin 5 receptor, alpha Protein, il5ra.L Protein, IL5RA Protein, il5ra Protein, Il5ra Protein
- 背景
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Background: Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA (CD125) is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported. IL5RA (CD125) is a T-cell-derived cytokine which is particularly important in the development of asthma for the lerminal differentiation, activation and survival of committed cosinophil precursors.
Synonym: Interleukin-5 receptor subunit alpha, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5R-alpha, IL-5RA, CD125, Il5ra, Il5r
- 分子量
- 36.8 kDa
- UniProt
- P21183
- 途径
- JAK/STAT Signaling
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