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IL18R1 Protein (His tag)

IL18R1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7196446
发货至: 中国
  • 抗原 See all IL18R1 蛋白
    IL18R1 (Interleukin 18 Receptor 1 (IL18R1))
    蛋白类型
    Recombinant
    宿主
    • 14
    • 8
    • 2
    • 1
    • 1
    大鼠
    资源
    • 11
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL18R1 protein is labelled with His tag.
    原理
    Recombinant Rat IL18R1 Protein (His Tag)
    序列
    Met1-Gly326
    产品特性
    A DNA sequence encoding the rat IL18R1 (D3ZRM2) (Met1-Gly326) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product IL18R1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL18R1 (Interleukin 18 Receptor 1 (IL18R1))
    别名
    IL18R1 (IL18R1 产品)
    别名
    CD218a Protein, CDw218a Protein, IL-1Rrp Protein, IL18RA Protein, IL1RRP Protein, IL-1R9 Protein, IL1R9 Protein, IL1RAPL-2 Protein, TIGIRR-1 Protein, Il18ralpha Protein, Il1rrp Protein, IL-18Ra Protein, IL18R1 Protein, interleukin 18 receptor 1 Protein, interleukin 1 receptor accessory protein like 2 Protein, IL18R1 Protein, IL1RAPL2 Protein, Il18r1 Protein
    背景

    Background: Interleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression is found in Hodgkin disease cell lines. This receptor is specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IL18R1 contains 3 Ig-like C2-type (immunoglobulin-like) domains and 1 TIR domain. It is a single-pass type I membrane protein. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The increased expression of IL18R1 may contribute pathogenically to disease and is therefore a potential therapeutic target. The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.

    Synonym: IL18R1

    分子量
    36.9 kDa
    UniProt
    D3ZRM2
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