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IL1RAPL1 Protein (AA 1-354) (His tag)

IL1RAPL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7196309
发货至: 中国
  • 抗原 See all IL1RAPL1 蛋白
    IL1RAPL1 (Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-354
    宿主
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    资源
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL1RAPL1 protein is labelled with His tag.
    原理
    Recombinant Human IL-1R8/IL1RAPL1 Protein (aa 1-354, His Tag)
    序列
    Met 1-Leu 354
    产品特性
    A DNA sequence encoding the human IL1R8 (NP_055086.1) extracellular domain (Met 1-Leu 354) was expressed with a C-terminal polyhistidine tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL1RAPL1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IL1RAPL1 (Interleukin 1 Receptor Accessory Protein-Like 1 (IL1RAPL1))
    别名
    IL-1R8/IL1RAPL1 (IL1RAPL1 产品)
    别名
    Il1rapl Protein, 6330532G10Rik Protein, C030039N24 Protein, IL1R8 Protein, IL1RAPL Protein, MRX34 Protein, OPHN4 Protein, TIGIRR-2 Protein, MRX10 Protein, MRX21 Protein, wu:fi18g04 Protein, zgc:152866 Protein, interleukin 1 receptor accessory protein-like 1 Protein, interleukin 1 receptor accessory protein like 1 Protein, interleukin 1 receptor accessory protein-like 1a Protein, interleukin 1 receptor accessory protein-like 1b Protein, Il1rapl1 Protein, IL1RAPL1 Protein, il1rapl1a Protein, il1rapl1b Protein
    背景

    Background: Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding of an as yet unidentified ligand, a transmembrane region, and an intracellular domain, which is likely to enable signalling via the NFkB pathway. The means of signalling is almost certain to be identical to that used by the IL1R family and the more distally related Toll protein. L1RAPL1 protein physically interacts via its 150 aa C-terminal domain with neuronal calcium sensor-1 (NCS-1), a protein widely expressed in neurons and the related chromaffin and PC12 cells. IL1RAPL1 is an integral membrane protein responsible for a nonsyndromic form of mental retardation (MR). It is suggested to affect human cognitive ability to some extent, especially the memory and concentration capability.

    Synonym: IL1R8,IL1RAPL,MRX10,MRX21,MRX34,OPHN4,TIGIRR-2

    分子量
    40 kDa
    NCBI登录号
    NP_055086
    途径
    Synaptic Membrane, Growth Factor Binding
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