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Quick Overview for IL1A Protein (AA 115-270) (ABIN7321259)
抗原
See all IL1A 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 115-270
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原理
- Recombinant Rat IL-1A/ IL-1α Protein
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序列
- Ser115-Ser270
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产品特性
- Recombinant Rat Interleukin-1 Alpha is produced by our E.coli expression system and the target gene encoding Ser115-Ser270 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Interleukin 1 alpha (IL1A) (Active) protein
IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (Active) proteinIL1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (AA 113-271) protein (Fc Tag)IL1A 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interleukin 1 alpha (IL1A) (AA 113-271) (Active) protein (His tag)IL1A 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 1 alpha (IL1A) (AA 113-271) (Active) proteinIL1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 1 alpha (IL1A) (AA 115-270) protein (His tag)IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
Interleukin 1 alpha (IL1A) (AA 115-270) (Active) protein (His tag)IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 1 alpha (IL1A) (AA 113-271) (Active) protein (His tag)IL1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 1 alpha (IL1A) (AA 115-270) (Active) protein (His tag)IL1A 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 1 alpha (IL1A) (AA 115-270) (Active) protein (His tag)IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by reducing SDS-PAGE. CC Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- IL-1A/ IL-1alpha
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背景
- Interleukin,Hematopoietin,IL1F1hematopoietin,IL1F,IL-1F,alpha,BAF,Hematopoietin-1,IL1,IL1 alpha,IL-1 alpha,IL1-A,IL-1A,IL1-ALPHA,IL1F1,IL-1F1,IL1F1hematopoietin-1,interleukin 1,interleukin-1 alpha,LAF,LEM,preinterleukin 1 alpha,pro-interleukin-1-alpha,Il1a,FAF,Hematopoietin 1,IL 1 alpha,IL 1A,IL1,IL1 ALPHA,IL1F1,Interleukin 1 alpha,LAF,LEM,Preinterleukin 1 alpha,Il1a,Interleukin 1 (IL-1) is a name that designates two proteins, IL-1αand IL-1β, which are the products of distinct genes, but which show approximately 25 % amino acid (aa) sequence identity and which recognize the same cell surface receptors. IL-1αand IL-1β are both synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17,000 Da. Neither precursor contains a typical hydrophobic signal peptide sequence and most of the precursor form of IL-1α remains in the cytosol of cells, although there is evidence for a membranebound form of the precursor form of IL-1α. Although IL-1 production is generally considered to be a consequence of inflammation, evidence suggests that IL-1 is also temporally upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. In response to classic stimuli produced by inflammatory agents, infections or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cells is seen.
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分子量
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Calculated MW: 17.9 kDa
Observed MW: 16 kDa
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基因ID
- 24493
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UniProt
- P16598
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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