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IFI30 Protein (His tag)

IFI30 宿主: 人 宿主: HEK-293 Cells Recombinant > 96 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317348
发货至: 中国
  • 抗原 See all IFI30 蛋白
    IFI30 (Interferon, gamma-Inducible Protein 30 (IFI30))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
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    • 1
    • 1
    HEK-293 Cells
    标记
    This IFI30 protein is labelled with His tag.
    原理
    Recombinant Human IFI30 Protein (His Tag)
    序列
    Met 1-Lys243
    产品特性
    A DNA sequence encoding the human IFI30 (P13284) (Met1-Lys243) with a C-terminal polyhistidine tag was expressed.
    纯度
    > 96 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IFI30 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IFI30 (Interferon, gamma-Inducible Protein 30 (IFI30))
    别名
    IFI30 (IFI30 产品)
    别名
    GILT Protein, wu:fb12b04 Protein, zgc:101752 Protein, IP30 Protein, IFI-30 Protein, interferon, gamma-inducible protein 30 Protein, IFI30, lysosomal thiol reductase Protein, interferon gamma inducible protein 30 Protein, ifi30 Protein, IFI30 Protein, LOC100304719 Protein, Ifi30 Protein
    背景

    Background: IFI30 belongs to the GILT family. This family includes the two characterised human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putative proteins with similarity to GILT. The aligned region contains three conserved cysteine residues. In addition, the two GILT sequences possess a C-X(2)-C motif that is shared by some of the other sequences in the family. This motif is thought to be associated with disulphide bond reduction. IFI30 is a lysosomal thiol reductase that can reduce protein disulfide bonds. It facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. It also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation. IFI30 may facilitate the complete unfolding of proteins destined for lysosomal degradation and plays an important role in antigen processing.

    Synonym: GILT,IFI-30,IFI30,IP-30,IP30

    分子量
    24.7 kDa
    UniProt
    P13284
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