ILKAP Protein (His tag)
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- 抗原 See all ILKAP 蛋白
- ILKAP (Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ILKAP protein is labelled with His tag.
- 原理
- Recombinant Human ILKAP Protein (His Tag)
- 序列
- Met 1-His 392
- 产品特性
- A DNA sequence encoding the human ILKAP (Q9H0C8) (Met 1-His 392) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 92 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ILKAP 蛋白
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Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP) (AA 293-392) protein (GST tag)
ILKAP 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP) (AA 1-392) protein (GST tag)ILKAP 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP) (AA 1-392) protein (Strep Tag)Crystallography grade ILKAP 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP) (AA 1-392) protein (Strep Tag)Crystallography grade ILKAP 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP) (AA 1-392), (full length) protein (His-SUMO Tag)ILKAP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP) protein (Myc-DYKDDDDK Tag)ILKAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ILKAP (Integrin-Linked Kinase-Associated Serine/threonine Phosphatase 2C (ILKAP))
- 别名
- ILKAP (ILKAP 产品)
- 别名
- MGC84595 Protein, MGC107938 Protein, ILKAP Protein, ILKAP2 Protein, ILKAP3 Protein, PP2C-DELTA Protein, 0710007A14Rik Protein, 1600009O09Rik Protein, ILK associated serine/threonine phosphatase Protein, ILK associated serine/threonine phosphatase L homeolog Protein, integrin-linked kinase-associated serine/threonine phosphatase Protein, integrin-linked kinase-associated serine/threonine phosphatase 2C Protein, ILKAP Protein, ilkap.L Protein, ilkap Protein, Ilkap Protein
- 背景
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Background: Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is cytoplasm protein which belongs to the PP2C family. ILKAP contains one PP2C-like domain. ILKAP is widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues. ILKAP may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. ILKAP selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. ILKAP inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation. Integrin-linked kinase ( ILK ) plays key roles in a variety of cell functions, including cell proliferation, adhesion and migration. Within the cell, ILK localizes to multiple sites, including the cytoplasm, focal adhesion complexes that mediate cell adhesion to extracellular substrates, as well as cell-cell junctions in epidermal keratinocytes. Nuclear ILK can be rapidly exported into the cytoplasm through a CRM1-dependent pathway, and its export is enhanced by the type 2C protein phosphatase ILKAP. Nuclear localization of ILK in epidermal keratinocytes is associated with increased DNA synthesis, which is sensitive to inhibition by ILKAP.
Synonym: ILKAP2;ILKAP3;PP2C-DELTA
- 分子量
- 44.3 kDa
- UniProt
- Q9H0C8
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