IDO2 Protein (His tag)
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- 抗原 See all IDO2 蛋白
- IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IDO2 protein is labelled with His tag.
- 原理
- Recombinant Human IDO2 Protein (His Tag)
- 序列
- Met14-Gly420
- 产品特性
- Recombinant Human IDO2 is produced by our E.coli expression system and the target gene encoding Met14-Gly420 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IDO2 蛋白
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Indoleamine 2,3-Dioxygenase 2 (IDO2) (AA 15-420) protein (His tag)
IDO2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Indoleamine 2,3-Dioxygenase 2 (IDO2) (AA 1-405) protein (Strep Tag)Crystallography grade IDO2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Indoleamine 2,3-Dioxygenase 2 (IDO2) (AA 1-420) protein (His tag)Crystallography grade IDO2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Indoleamine 2,3-Dioxygenase 2 (IDO2) (AA 1-407), (full length) protein (His-SUMO Tag)IDO2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Indoleamine 2,3-Dioxygenase 2 (IDO2) (AA 1-407), (full length) protein (His tag)IDO2 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
Indoleamine 2,3-Dioxygenase 2 (IDO2) proteinIDO2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
Indoleamine 2,3-Dioxygenase 2 (IDO2) protein (Myc-DYKDDDDK Tag)IDO2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 10 % Glycerol,1 mMEDTA,250 mM NaCl, pH 8.0.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
- 别名
- IDO2 (IDO2 产品)
- 别名
- INDOL1 Protein, Indol1 Protein, AI265623 Protein, C230043N17Rik Protein, Ido-2 Protein, indoleamine 2,3-dioxygenase 2 Protein, IDO2 Protein, Ido2 Protein
- 背景
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Background: Indoleamine 2,3-dioxygenase-like protein 1(IDO2) belongs to the indoleamine 2,3-dioxygenase family. IDO2 can be detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. It also expressed at low level in testis and thyroid but not expressed in the majority of human tumor samples. IDO2 catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. It involved in immune regulation. IDO1 and IDO2 are 2 distinct enzymes which catalyze the same reaction. IDO2 affinity for tryptophan is much lower than that of IDO1. 50 % of Caucasians harbor polymorphisms which abolish IDO2 enzymatic activity. IDO2 is expressed in human tumors in an inactive form: tryptophan degradation is entirely provided by IDO1 in these cells. IDO2 may play a role as a negative regulator of IDO1 by competing for heme-binding with IDO1. Low efficiency IDO2 enzymes have been conserved throughout vertebrate evolution, whereas higher efficiency IDO1 enzymes are dispensable in many lower vertebrate lineages. IDO1 may have arisen by gene duplication of a more ancient proto-IDO gene before the divergence of marsupial and eutherian (placental) mammals.
Synonym: INDOL1
- 分子量
- 46.5 kDa
- UniProt
- Q6ZQW0
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