HAPLN1 Protein (His tag)
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- 抗原 See all HAPLN1 蛋白
- HAPLN1 (Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This HAPLN1 protein is labelled with His tag.
- 原理
- Recombinant Human HAPLN1 Protein (His Tag)
- 序列
- Met 1-Asn 354
- 产品特性
- A DNA sequence encoding the human HAPLN1 (NP_001875.1) (Met 1-Asn 354) was expressed with a C-terminal polyhistidine tag.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HAPLN1 蛋白
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Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) (AA 1-354) protein (GST tag)
HAPLN1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) (AA 16-354) protein (His tag)HAPLN1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % by SDS - PAGE SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- HAPLN1 (Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1))
- 别名
- HAPLN1 (HAPLN1 产品)
- 别名
- crtl1 Protein, hapln1 Protein, wu:fc26f11 Protein, wu:fc37g04 Protein, wu:fc50e12 Protein, wu:fc55h01 Protein, CRTL1 Protein, LP Protein, BB099155 Protein, CLP Protein, Crtl1 Protein, Crtl1l Protein, LP-1 Protein, CTRL1 Protein, hyaluronan and proteoglycan link protein 1 Protein, hyaluronan and proteoglycan link protein 1a Protein, HAPLN1 Protein, hapln1a Protein, Hapln1 Protein
- 背景
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Background: Hyaluronan (HA) is a high MW glycosaminoglycan significantly involved in the formation and stability of extracellular matrix via its association with specific HA-binding proteins. HAPLN1, also known as CRTL1 (Cartilage Link Protein 1, cLP ) and link protein, is a member of HA-binding protein (hyaladherins) family, and contains a common structural domain of about 100 amino acids that is termed a Link module with two α-helices and two antiparallel β-sheets. HAPLN1/CRTL1 stabilizes the interaction between hyaluronan (HA) and versican, two extracellular matrix components essential for cardiac development. Link module superfamily can be divided into three subgroups, and the HAPLN family are C domain-type proteins that have an extended structure with one N-terminal V-type Ig-like domain followed by two link modules. In cartilage, aggrecan forms - cLP stabilized aggregates with HA that provides the tissue with its load bearing properties. HAPLN1 is a component of follicular matrix, was shown to enhance cumulus-oocyte complex (COC) expansion in vitro. HAPLN1 may promote periovulatory granulosa cell survival, which would facilitate their differentiation into luteal cells.
Synonym: CRTL1
- 分子量
- 40 kDa
- NCBI登录号
- NP_001875
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