HSPB11 Protein (His tag)
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- 抗原 See all HSPB11 蛋白
- HSPB11 (Heat Shock Protein Family B (Small), Member 11 (HSPB11))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This HSPB11 protein is labelled with His tag.
- 原理
- Recombinant Human HSPB11 Protein (His Tag)
- 序列
- Met 1-Ser144
- 产品特性
- Recombinant Human Heat Shock Protein beta-11 is produced by our E.coli expression system and the target gene encoding Met1-Ser144 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HSPB11 蛋白
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Heat Shock Protein Family B (Small), Member 11 (HSPB11) (AA 1-144) protein (His tag)
HSPB11 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Heat Shock Protein Family B (Small), Member 11 (HSPB11) protein (Myc-DYKDDDDK Tag)HSPB11 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 2 mM DTT, 10 % Glycerol, pH 8.0.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- HSPB11 (Heat Shock Protein Family B (Small), Member 11 (HSPB11))
- 别名
- HSPB11 (HSPB11 产品)
- 别名
- C1orf41 Protein, HSPCO34 Protein, IFT25 Protein, PP25 Protein, 2900042B11Rik Protein, cb02d06 Protein, mg:cb02d06 Protein, heat shock protein family B (small), member 11 Protein, heat shock protein family B (small) member 11 Protein, heat shock protein, alpha-crystallin-related, b11 Protein, Hspb11 Protein, HSPB11 Protein, hspb11 Protein
- 背景
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Background: Heat Shock Protein β-11 (HSPB11) is a stress-responsive protein that is required to deal with proteotoxic stresses. HSPB11 is composed of an IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT20 and is detected in placenta. HSPB11 has beeb shown to form oligomeric complexes and prevent the aggregation of in vitro denaturated aldolase and glyceraldehyde-3-phosphate dehydrogenase in accordance with the chaperone model of HSPB1 and HSPB5. HSPB11 overexpression protected against etoposide-induced cell death that correlated with a decreased release of mitochondrial Cytochrome C into the cytosol. Inhibition of HSP90 function completely abrogated the protective effect of HSPB11. This data suggests that at least in the case of HSPB11, interaction with other chaperone machines besides HSPA1A may contribute to functional specificity and cellular functioning.
Synonym: Heat Shock Protein Beta-11, Hspb11, Placental Protein 25, PP25, HSPB11, C1orf41
- 分子量
- 18.5 kDa
- UniProt
- Q9Y547
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