GTPase NRas Protein (NRAS) (His tag)
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Quick Overview for GTPase NRas Protein (NRAS) (His tag) (ABIN7317421)
抗原
See all GTPase NRas (NRAS) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This GTPase NRas protein is labelled with His tag.
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原理
- Recombinant Human NRAS Protein (His Tag)
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序列
- Met 1-Cys186
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产品特性
- A DNA sequence encoding the mature form of human NRAS (P01111) (Met1-Cys186) was expressed with a polyhistidine tag at the N-terminus.
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GTPase NRas (NRAS) (AA 1-186) protein (His tag)
NRAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
GTPase NRas (NRAS) (AA 90-189) protein (GST tag)NRAS 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
GTPase NRas (NRAS) (AA 1-189) protein (GST tag)NRAS 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
GTPase NRas (NRAS) (AA 1-186) proteinNRAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS
GTPase NRas (NRAS) protein (Myc-DYKDDDDK Tag)NRAS 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 20 mM Tris, 0.1M NaCl, 10 % Glycerol, pH 7.5
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- GTPase NRas (NRAS)
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别名
- NRAS
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背景
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Background: NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it is activated in HL60, a promyelocytic leukemia line. The mammalian ras gene family consists of the harvey and kirsten ras genes (HRAS and KRAS), an inactive pseudogene of each (c-Hras2 and c-Kras1) and the N-ras gene. They differ significantly only in the C-terminal 40 amino acids. These ras genes have GTP/GDP binding and GTPase activity, and their normal function may be as G-like regulatory proteins involved in the normal control of cell growth. The NRAS gene specifies two main transcripts of 2Kb and 4.3Kb. The difference between the two transcripts is a simple extension through the termination site of the 2Kb transcript. The NRAS gene consists of seven exons (-I, I, II, III, IV, V, VI).Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: ALPS4;CMNS;N-ras;NCMS;NRAS1;NS6
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分子量
- 23 kDa
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UniProt
- P01111
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途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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