GFER Protein (His tag)
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- 抗原 See all GFER 蛋白
- GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This GFER protein is labelled with His tag.
- 原理
- Recombinant Human GFER Protein (His Tag)
- 序列
- Met 1-Asp125
- 产品特性
- Recombinant Human Growth Factor, Augmenter of Liver Regeneration is produced by our E.coli expression system and the target gene encoding Met1-Asp125 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GFER 蛋白
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Growth Factor, Augmenter of Liver Regeneration (GFER) (AA 1-125) protein (GST tag)
GFER 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Factor, Augmenter of Liver Regeneration (GFER) (AA 1-205) protein (Strep Tag)Crystallography grade GFER 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Growth Factor, Augmenter of Liver Regeneration (GFER) (AA 1-198) protein (Strep Tag)Crystallography grade GFER 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Growth Factor, Augmenter of Liver Regeneration (GFER) protein (Myc-DYKDDDDK Tag)GFER 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))
- 别名
- GFER (GFER 产品)
- 别名
- ALR Protein, ERV1 Protein, HERV1 Protein, HPO Protein, HPO1 Protein, HPO2 Protein, HSS Protein, Alr Protein, growth factor, augmenter of liver regeneration Protein, growth factor, augmenter of liver regeneration L homeolog Protein, GFER Protein, Gfer Protein, gfer.L Protein
- 背景
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Background: GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. Isoform 2 may act as an autocrine hepatotrophic growth factor promoting liver regeneration. GFER could also induce the expression of S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases (ODC). S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases play an important role in the synthesis of polyamines.
Synonym: FAD-linked sulfhydryl oxidase ALR,GFER,Augmenter of liver regeneration,hERV1,Hepatopoietin,GFER,ALR,HERV1,HPO
- 分子量
- 17.3 kDa
- UniProt
- P55789
- 途径
- SARS-CoV-2 Protein Interactome
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