GAP43 Protein (His tag)
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- 抗原 See all GAP43 蛋白
- GAP43 (Growth Associated Protein 43 (GAP43))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This GAP43 protein is labelled with His tag.
- 原理
- Recombinant Human GAP43/Neuromodulin Protein (His Tag)
- 序列
- Met 1-Ala 238
- 产品特性
- A DNA sequence encoding the human GAP43 (P17677) (Met 1-Ala 238) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 96 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GAP43 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- GAP43 (Growth Associated Protein 43 (GAP43))
- 别名
- GAP43/Neuromodulin (GAP43 产品)
- 别名
- B-50 Protein, PP46 Protein, Basp2 Protein, GAP-43 Protein, b-50 Protein, gap-43 Protein, gap43b Protein, pp46 Protein, cb310 Protein, gap Protein, gap43 Protein, gap43a Protein, growth associated protein 43 Protein, growth associated protein 43 L homeolog Protein, growth associated protein 43 S homeolog Protein, GAP43 Protein, Gap43 Protein, gap43.L Protein, gap43 Protein, gap43.S Protein
- 背景
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Background: Neuromodulin, also known as Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, pp46 and GAP43, is a cell membrane protein which belongs to the neuromodulin family. Neuromodulin / GAP43 contains one IQ domain. Neuromodulin / GAP43 is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Neuromodulin / GAP43 is involved in neurite outgrowth, a crucial process for the differentiation of neurons. The sudden infant death syndrome (SIDS) is the main cause of postneonatal infant death and its cause is still unknown. Neuromodulin / GAP43 is a marker of synaptic plasticity and is critical for normal development of the serotonergic innervation. Neuromodulin / GAP43 is a major cortical cytoskeleton-associated and calmodulin binding protein that is widely and abundantly expressed during development, maintained in selected brain structures in the adult, and reinduced during nerve regeneration. CAP23 and GAP43 are functionally related intrinsic determinants of anatomical plasticity. These proteins function by locally promoting subplasmalemmal actin cytoskeleton accumulation.
Synonym: B-50;PP46
- 分子量
- 26.2 kDa
- UniProt
- P17677
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