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GAP43 Protein (His tag)

GAP43 宿主: 人 宿主: HEK-293 Cells Recombinant > 96 % as determined by reducing SDS-PAGE.
产品编号 ABIN7195999
发货至: 中国
  • 抗原 See all GAP43 蛋白
    GAP43 (Growth Associated Protein 43 (GAP43))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 10
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This GAP43 protein is labelled with His tag.
    原理
    Recombinant Human GAP43/Neuromodulin Protein (His Tag)
    序列
    Met 1-Ala 238
    产品特性
    A DNA sequence encoding the human GAP43 (P17677) (Met 1-Ala 238) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 96 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GAP43 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    GAP43 (Growth Associated Protein 43 (GAP43))
    别名
    GAP43/Neuromodulin (GAP43 产品)
    别名
    B-50 Protein, PP46 Protein, Basp2 Protein, GAP-43 Protein, b-50 Protein, gap-43 Protein, gap43b Protein, pp46 Protein, cb310 Protein, gap Protein, gap43 Protein, gap43a Protein, growth associated protein 43 Protein, growth associated protein 43 L homeolog Protein, growth associated protein 43 S homeolog Protein, GAP43 Protein, Gap43 Protein, gap43.L Protein, gap43 Protein, gap43.S Protein
    背景

    Background: Neuromodulin, also known as Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, pp46 and GAP43, is a cell membrane protein which belongs to the neuromodulin family. Neuromodulin / GAP43 contains one IQ domain. Neuromodulin / GAP43 is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Neuromodulin / GAP43 is involved in neurite outgrowth, a crucial process for the differentiation of neurons. The sudden infant death syndrome (SIDS) is the main cause of postneonatal infant death and its cause is still unknown. Neuromodulin / GAP43 is a marker of synaptic plasticity and is critical for normal development of the serotonergic innervation. Neuromodulin / GAP43 is a major cortical cytoskeleton-associated and calmodulin binding protein that is widely and abundantly expressed during development, maintained in selected brain structures in the adult, and reinduced during nerve regeneration. CAP23 and GAP43 are functionally related intrinsic determinants of anatomical plasticity. These proteins function by locally promoting subplasmalemmal actin cytoskeleton accumulation.

    Synonym: B-50;PP46

    分子量
    26.2 kDa
    UniProt
    P17677
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