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GPC1 Protein (His tag)

GPC1 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by SDS-PAGE Active
产品编号 ABIN7320535
发货至: 中国
  • 抗原 See all GPC1 蛋白
    GPC1 (Glypican 1 (GPC1))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 11
    • 5
    • 1
    小鼠
    资源
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This GPC1 protein is labelled with His tag.
    原理
    Recombinant Mouse Glypican-1/GPC1 Protein (His Tag)(Active)
    序列
    Asp24-Ser529
    产品特性
    Recombinant Mouse Glypican-1 is produced by our Mammalian expression system and the target gene encoding Asp24-Ser529 is expressed with a 6His tag at the C-terminus.
    纯度
    > 90 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human FGFb(Cat: PKSH032437) at 2μg/ml(100 μl/well) can bind Mouse GPC1-His. The ED50 of Mouse GPC1-His is 786 ng/ml .
    Top Product
    Discover our top product GPC1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    GPC1 (Glypican 1 (GPC1))
    别名
    Glypican-1/GPC1 (GPC1 产品)
    别名
    gpc1 Protein, zgc:63947 Protein, GPC1 Protein, Glypican-1 Protein, glypican Protein, AI462976 Protein, HSPG M12 Protein, HSPGM12 Protein, glypican 1b Protein, glypican 1 Protein, gpc1b Protein, GPC1 Protein, gpc1 Protein, Gpc1 Protein
    背景

    Background: Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

    Synonym: Glypican-1,Gpc1

    分子量
    56.7 kDa
    UniProt
    Q9QZF2
    途径
    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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