GFPT1 蛋白
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- 抗原 See all GFPT1 蛋白
- GFPT1 (Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human GFPT1/GFAT Protein
- 序列
- Gln 332-Glu 699
- 产品特性
- The sequence corresponding to amino acids (Gln 332-Glu 699) of human GFAT (AAA58502.1) was expressed and purified with two amino acids (Gly & Pro) at the N-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GFPT1 蛋白
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Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) (AA 1-681) protein (GST tag)
GFPT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) (AA 2-699) protein (His tag)Crystallography grade GFPT1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) (AA 2-697) protein (His tag)Crystallography grade GFPT1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) (AA 332-699) protein (His tag)GFPT1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) protein (Myc-DYKDDDDK Tag)GFPT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- GFPT1 (Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1))
- 别名
- GFPT1/GFAT (GFPT1 产品)
- 别名
- gfat Protein, 2810423A18Rik Protein, AI324119 Protein, AI449986 Protein, GFA Protein, GFAT Protein, GFAT1 Protein, GFAT1m Protein, Gfpt Protein, CMSTA1 Protein, GFAT 1 Protein, GFPT Protein, GFPT1L Protein, MSLG Protein, glutamine--fructose-6-phosphate transaminase 1 Protein, glutamine--fructose-6-phosphate transaminase 1 S homeolog Protein, glutamine fructose-6-phosphate transaminase 1 Protein, GFPT1 Protein, gfpt1.S Protein, Gfpt1 Protein
- 背景
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Background: Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosamine biosynthesis pathway (HBP) in mammals. GFAT transfers the amino group from the L-glutamine amide to the D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. GFAT exists as a homotetramer in cytoplasm, and is proposed to be most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. The full length of human GFAT contains 1 glutamine amidotransferase type-2 domain which catalyzes amide nitrogen transfer from glutamine to the appropriate substrate, and 2 SIS (Sugar Isomerase) domains found in many phosphosugar isomerases and phosphosugar binding proteins.Two isoforms of gfat have been identified: GFAT1 is predominantly expressed in skeletal muscle, whereas GFAT2 is expressed mainly in the central nervous system.
Synonym: CMSTA1,GFA,GFAT,GFAT1,GFAT1m,GFPT,GFPT1L,MSLG
- 分子量
- 41.5 kDa
- 途径
- ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process
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