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GAD Protein (His tag)

GAD1 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317359
发货至: 中国
  • 抗原 See all GAD (GAD1) 蛋白
    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 4
    • 3
    资源
    • 7
    • 2
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    标记
    This GAD protein is labelled with His tag.
    原理
    Recombinant Human GAD67/GAD1 Protein (His Tag)
    序列
    Met 1-Leu 594
    产品特性
    A DNA sequence encoding the human GAD1 (Q99259-1) (Met 1-Leu 594) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 92 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GAD1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.5
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
    别名
    GAD67/GAD1 (GAD1 产品)
    别名
    CPSQ1 Protein, GAD Protein, SCP Protein, GAD-67 Protein, cpsq1 Protein, gad1 Protein, gad1-A Protein, gad67 Protein, GAD67 Protein, GAD1 Protein, GLUTAMATE DECARBOXYLASE Protein, GLUTAMATE DECARBOXYLASE 1 Protein, MKP11.30 Protein, MKP11_30 Protein, glutamate decarboxylase Protein, EP10 Protein, GAD25 Protein, GAD44 Protein, Gad-1 Protein, Gad67 Protein, glutamate decarboxylase 1 Protein, glutamate decarboxylase 1 L homeolog Protein, glutamate decarboxylase Protein, glutamate decarboxylase 1b Protein, GAD1 Protein, gad1.1.L Protein, GAD Protein, Gad1 Protein, gad1b Protein
    背景

    Background: Glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform and GAD1, is a member of the group II decarboxylase family. GAD1 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker. GAD1 isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. Tissue-specific markers are useful for identification of tumour type in advanced cancers of unknown origin. In plants, as in most eukaryotes, glutamate decarboxylase catalyses the synthesis of GABA. Root-specific calcium/calmodulin-regulated GAD1 plays a major role in GABA synthesis in plants under normal growth conditions and in response to stress. Defects in GAD1 are the cause of cerebral palsy spastic quadriplegic type 1 (CPSQ1)which is a non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals manifest symmetrical, non-progressive spasticity and no adverse perinatal history or obvious underlying alternative diagnosis.

    Synonym: CPSQ1;GAD;SCP

    分子量
    68.3 kDa
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