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Intrinsic Factor Protein (His tag)

GIF 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317227
发货至: 中国
  • 抗原 See all Intrinsic Factor (GIF) 蛋白
    Intrinsic Factor (GIF) (Gastric Intrinsic Factor (Vitamin B Synthesis) (GIF))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 3
    • 2
    • 1
    • 1
    资源
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This Intrinsic Factor protein is labelled with His tag.
    原理
    Recombinant Human Gastric intrinsic factor/GIF Protein (His Tag)
    序列
    Met 1-Tyr417
    产品特性
    A DNA sequence encoding the human GIF (P27352-1) (Met1-Tyr417) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GIF 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Intrinsic Factor (GIF) (Gastric Intrinsic Factor (Vitamin B Synthesis) (GIF))
    别名
    Gastric intrinsic factor/GIF (GIF 产品)
    别名
    GIF Protein, IF Protein, IFMH Protein, INF Protein, TCN3 Protein, AV073125 Protein, gastric intrinsic factor Protein, GIF Protein, Gif Protein
    背景

    Background: Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to gastric intrinsic factor. This new complex travels to the ileum, where special epithelial cells endocytose them. Inside the cell, B12 dissociates once again and binds to another protein, transcobalamin II. The new complex can exit the epithelial cells to enter the liver.

    Synonym: IF,IFMH,INF,TCN3

    分子量
    44.8 kDa
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