FLRT2 Protein (His tag)
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- 抗原 See all FLRT2 蛋白
- FLRT2 (Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FLRT2 protein is labelled with His tag.
- 原理
- Recombinant Human FLRT2 Protein (His Tag)(Active)
- 序列
- Met 1-Ser 539
- 产品特性
- A DNA sequence encoding the human FLRT2 (O43155) extracellular domain (Met 1-Ser 539) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 98 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of Neuro-2A mouse neuroblastoma cells.When cells are added to coated plates(5μg/mL, 100μL/well), approximately 50%-70% will adhere after 1 hour at 37°C.
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- Discover our top product FLRT2 蛋白
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Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2) (Active) protein (His tag)
FLRT2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2) (AA 36-541) protein (His tag)Crystallography grade FLRT2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2) (AA 36-540) protein (His tag)Crystallography grade FLRT2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2) (AA 36-660) protein (rho-1D4 tag)Crystallography grade FLRT2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2) (AA 36-660) protein (rho-1D4 tag)Crystallography grade FLRT2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2) protein (Myc-DYKDDDDK Tag)FLRT2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FLRT2 (Fibronectin Leucine Rich Transmembrane Protein 2 (FLRT2))
- 别名
- FLRT2 (FLRT2 产品)
- 别名
- fibronectin leucine rich transmembrane protein 2 S homeolog Protein, fibronectin leucine rich transmembrane protein 2 Protein, flrt2.S Protein, flrt2 Protein, FLRT2 Protein, Flrt2 Protein
- 背景
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Background: Fibronectin Leucine-Rich Transmembrane (FLRT) proteins are glycosylated membrane proteins expressed at the cell surface which localise in a homophilic manner to cell-cell contacts expressing the focal adhesion marker vinculin. FLRT1, FLRT2, and FLRT3, the three genes encode putative type I transmembrane proteins, each containing 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT family members may function in cell adhesion and/or receptor signalling. Each member of the FLRT family has a distinct, highly regulated expression pattern, as was seen for the NLRR family. FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome, suggesting that interaction with FGF signalling may be a general property of FLRT proteins. All FLRTs can interact with FGFR1 and FLRTs can be induced by the activation of FGF signalling by FGF-2. FLRT proteins have a dual role, promoting FGF signalling and modulating homotypic cell adhesion. FLRT2 played critical roles in craniofacial development, and it was also present in the vomero-nasal organ, mandibular primodia, and the posterior aspects of the unfused and fused secondary palatal shelves.
Synonym: Leucine-Rich Repeat Transmembrane Protein FLRT2, Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 2, FLRT2, KIAA0405
- 分子量
- 57.7 kDa
- UniProt
- O43155
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