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FGF17 Protein (His tag)

FGF17 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE Active
产品编号 ABIN7320525
发货至: 中国
  • 抗原 See all FGF17 蛋白
    FGF17 (Fibroblast Growth Factor 17 (FGF17))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 8
    • 3
    • 1
    • 1
    小鼠
    资源
    • 8
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This FGF17 protein is labelled with His tag.
    原理
    Recombinant Mouse FGF-17 Protein (His Tag)(Active)
    序列
    Thr23-Thr216
    产品特性
    Recombinant Mouse Fibroblast Growth Factor 17 is produced by our E.coli expression system and the target gene encoding Thr23-Thr216 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured in a cell proliferation assay using Balb/3T3 mouse fibroblast cells. The ED50 for this effect is 1.26 ug/ml, in the presence of 10 μg/mL heparin.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl,EDTA,DTT, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    FGF17 (Fibroblast Growth Factor 17 (FGF17))
    别名
    FGF-17 (FGF17 产品)
    别名
    FGF17 Protein, FGF-13 Protein, HH20 Protein, fgf17b Protein, zgc:101759 Protein, fibroblast growth factor 17 Protein, FGF17 Protein, Fgf17 Protein, fgf17 Protein
    背景

    Background: FGF-17 is a member of the fibroblast growth factor (FGF) family. FGFs share 30 70 % amino acid (aa) identity in a conserved, approximately 120 amino acid core domain. FGFs play multiple roles in biological functions, including angiogenesis, mitogenesis, cell differentiation and wound repair. FGF17 plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. It is also expressed in hindgut, parts of the developing skeleton, tail bud, major arteries, and heart. In many of these areas, it is expressed along with FGF-8, but slightly later. It is required for normal brain development.

    Synonym: Fibroblast growth factor 17, FGF-17,fgf17

    分子量
    23.7 kDa
    UniProt
    P63075
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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