EDEM2 Protein (His tag)
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- 抗原 See all EDEM2 蛋白
- EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This EDEM2 protein is labelled with His tag.
- 原理
- Recombinant Human EDEM2/C20orf31 Protein (His Tag)
- 序列
- Met 1-Lys492
- 产品特性
- A DNA sequence encoding the human EDEM2 (AAH01371.1) (Met1-Lys492) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product EDEM2 蛋白
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ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2) (AA 1-578) protein (GST tag)
EDEM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2) (AA 479-578) protein (GST tag)EDEM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2) (AA 22-578) protein (His tag)Crystallography grade EDEM2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))
- 别名
- EDEM2/C20orf31 (EDEM2 产品)
- 别名
- C20orf31 Protein, C20orf49 Protein, bA4204.1 Protein, 9530090G24Rik Protein, AI327354 Protein, RGD1303074 Protein, MGC88910 Protein, DKFZp459A0314 Protein, ER degradation enhancing alpha-mannosidase like protein 2 Protein, ER degradation enhancer, mannosidase alpha-like 2 Protein, EDEM2 Protein, Edem2 Protein, edem2 Protein
- 背景
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Background: EDEM2, also known as C20orf31, belongs to a family of proteins involved in ER-associated degradation (ERAD) of glycoproteins. In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome. Early in this pathway, a proposed lumenal ER lectin, EDEM, recognizes misfolded glycoproteins in the ER, disengages the nascent molecules from the folding pathway, and facilitates their targeting for disposal. In humans there are a total of three EDEM homologs. The amino acid sequences of these proteins are different from other lectins but are closely related to the Class I mannosidases (family 47 glycosidases). EDEM2 is one of the EDEM homologs. Overexpression of EDEM2 accelerates the degradation of misfolded alpha1-antitrypsin, indicating that the protein is involved in ERAD.
Synonym: bA4204.1,C20orf31,C20orf49,UNQ573/PRO1135
- 分子量
- 54 kDa
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