EpCAM Protein (His tag)
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- 抗原 See all EpCAM (EPCAM) 蛋白
- EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This EpCAM protein is labelled with His tag.
- 原理
- Recombinant Human EpCAM/TROP-1 Protein (His Tag)(Active)
- 序列
- Met 1-Lys265
- 产品特性
- A DNA sequence encoding the extracellular domain (Met 1-Lys265) of human EpCAM (NP_002345.1) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 96 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of NIH-3T3 mouse embryonic fibroblast cells. When cells are added to EpCAM-His coated plates (1.25μg/mL, 100μL/well), approximately >40% will adhere specifically after 30 minutes at 37°C.
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- Discover our top product EPCAM 蛋白
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Epithelial Cell Adhesion Molecule (EPCAM) (AA 24-265) protein (His-Avi Tag,Biotin)
EPCAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epithelial Cell Adhesion Molecule (EPCAM) (AA 24-265) protein (Fc Tag)EPCAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epithelial Cell Adhesion Molecule (EPCAM) (AA 24-265) protein (His tag)EPCAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epithelial Cell Adhesion Molecule (EPCAM) (AA 24-265) protein (His tag)EPCAM 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epithelial Cell Adhesion Molecule (EPCAM) (AA 24-265) protein (His-DYKDDDDK-Strep II Tag)EPCAM 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Epithelial Cell Adhesion Molecule (EPCAM) (Active) protein (Fc Tag)EPCAM 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Epithelial Cell Adhesion Molecule (EPCAM) protein (His tag)EPCAM 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by reducing SDS-PAGE.
Epithelial Cell Adhesion Molecule (EPCAM) (AA 118-314) protein (His tag)EPCAM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Epithelial Cell Adhesion Molecule (EPCAM) (AA 1-314) protein (GST tag)EPCAM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Epithelial Cell Adhesion Molecule (EPCAM) protein (His tag)EPCAM 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
- 别名
- EpCAM/TROP-1 (EPCAM 产品)
- 别名
- DIAR5 Protein, EGP-2 Protein, EGP314 Protein, EGP40 Protein, ESA Protein, HNPCC8 Protein, KS1/4 Protein, KSA Protein, M4S1 Protein, MIC18 Protein, MK-1 Protein, TACSTD1 Protein, TROP1 Protein, ECS-1 Protein, ECS1 Protein, ESA1 Protein, M17S1 Protein, EGP Protein, Ep-CAM Protein, sb:cb6 Protein, tacstd Protein, wu:fj17g02 Protein, zgc:110304 Protein, zgc:77119 Protein, tacstd1 Protein, MGC80540 Protein, EPCAM Protein, egp Protein, ksa Protein, m4s1 Protein, mk-1 Protein, cd326 Protein, egp40 Protein, mic18 Protein, trop1 Protein, ep-cam Protein, hegp-2 Protein, co17-1a Protein, ga733-2 Protein, CD326 Protein, Egp314 Protein, EpCAM1 Protein, GA733-2 Protein, Ly74 Protein, Tacsd1 Protein, Tacstd1 Protein, gp40 Protein, epithelial cell adhesion molecule Protein, flotillin 2 Protein, epithelial cell adhesion molecule S homeolog Protein, EPCAM Protein, FLOT2 Protein, epcam Protein, epcam.S Protein, Epcam Protein
- 背景
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Background: Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type â… transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: DIAR5;EGP-2;EGP314;EGP40;ESA;HNPCC8;KS1/4;KSA;M4S1;MIC18;MK-1;TACSTD1;TROP-1;TROP1
- 分子量
- 29 kDa
- NCBI登录号
- NP_002345
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