EPHA1 Protein (His tag)
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- 抗原 See all EPHA1 蛋白
- EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This EPHA1 protein is labelled with His tag.
- 原理
- Recombinant Mouse EphA1 Protein (His Tag)(Active)
- 序列
- Met 1-Glu 548
- 产品特性
- A DNA sequence encoding the extracellular domain of mouse EPHA1 (Q60750) (Met 1-Glu 548) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 97 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized mouse EPHA1-His at 10 μg/ml (100 μl/well) can bind mouse EFNA1-Fc ), The EC50 of mouse EFNA1-Fc is 21.3-49.8 ng/ml.
- Top Product
- Discover our top product EPHA1 蛋白
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Ephrin Type A Receptor 1 (EPHA1) (AA 394-500) protein (GST tag)
EPHA1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
- 别名
- EphA1 (EPHA1 产品)
- 别名
- EPH Protein, EPHT Protein, EPHT1 Protein, 5730453L17Rik Protein, AL033318 Protein, Eph Protein, Esk Protein, EPHA9 Protein, EPH receptor A1 Protein, Eph receptor A1 Protein, EPHA1 Protein, Epha1 Protein
- 背景
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Background: EPHA1 or EPH receptor A1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. An important role of Eph receptors and their ligands ephrins is to mediate cell-contact-dependent repulsion. Eph receptors and ephrins also act at boundaries to channel neuronal growth cones along specific pathways, restrict the migration of neural crest cells, and via bidirectional signaling prevent intermingling between hindbrain segments. Eph receptors and ephrins can also trigger an adhesive response of endothelial cells and are required for the remodeling of blood vessels. Eph receptors and ephrins have emerged as key regulators of the repulsion and adhesion of cells that underlie the establishment, maintainence, and remodeling of patterns of cellular organization. The ephrins and Eph receptors are implicated as positional labels that may guide the development of neural topographic maps.
Synonym: 5730453L17Rik,AL033318,Eph,Esk
- 分子量
- 58.6 kDa
- UniProt
- Q60750
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