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RNASE3 Protein (His tag)

ECP 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318990
发货至: 中国
  • 抗原 See all RNASE3 (ECP) 蛋白
    RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 3
    • 2
    • 1
    • 1
    资源
    • 5
    • 3
    • 1
    • 1
    人细胞
    标记
    This RNASE3 protein is labelled with His tag.
    原理
    Recombinant Human Ribonuclease 3/RNASE3 Protein (His Tag)
    序列
    Arg28-Ile160
    产品特性
    Recombinant Human Ribonuclease 3 is produced by our Mammalian expression system and the target gene encoding Arg28-Ile160 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ECP 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mMDTT,10 % Glycerol, pH 7.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))
    别名
    Ribonuclease 3/RNASE3 (ECP 产品)
    别名
    ECP Protein, RNS3 Protein, ribonuclease A family member 3 Protein, RNASE3 Protein
    背景

    Background: Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

    Synonym: Eosinophil Cationic Protein, ECP, Ribonuclease 3, RNase 3, RNASE3, ECP, RNS3

    分子量
    16.6 kDa
    UniProt
    P12724
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