ERAP2 Protein (His tag)
-
- 抗原 See all ERAP2 蛋白
- ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This ERAP2 protein is labelled with His tag.
- 原理
- Recombinant Human LRAP/ERAP2 Protein (His Tag)(Active)
- 序列
- Ala 56-Thr 960
- 产品特性
- A DNA sequence encoding the lumenal domain of human ERAP2 (NP_071745.1) (Ala 56-Thr 960) was expressed with a polyhistidine tag at the N-terminus.
- 纯度
- > 98 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to cleave the fluorogenic peptide substrate, Arg-7-amido-4-methylcoumarin (Arg-AMC). The specific activity is >50 pmoles/min/μg.
- Top Product
- Discover our top product ERAP2 蛋白
-
Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) (AA 1-350) protein (GST tag)
ERAP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) (AA 1-960) protein (Strep Tag)Crystallography grade ERAP2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) (AA 41-960) protein (His tag)Crystallography grade ERAP2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 12.5 mM Tris, 75 mM NaCl, pH 7.5, 50 % glycercol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
- 别名
- LRAP/ERAP2 (ERAP2 产品)
- 别名
- L-RAP Protein, LRAP Protein, ERAP2 Protein, zgc:172163 Protein, endoplasmic reticulum aminopeptidase 2 Protein, ERAP2 Protein, erap2 Protein
- 背景
-
Background: Leukocyte-derived arginine aminopeptidase (LRAP), also known as endoplasmic reticulum-aminopeptidase 2 (ERAP2), is the second identified aminopeptidase localized in the in the lumenal side of endoplasmic reticulum (ER) processing antigenic peptides presented to major histocompatibility complex (MHC) class I molecules. It is a 960-amino acid protein with significant homology to placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase. LRAP preferentially hydrolyzes the basic residues Arg and Lys, and contains the HEXXH(X)18E zinc-binding motif, which is the characteristic of the M1 family of zinc metallopeptidases which also includes PILS/ARTS1/ERAP1 and LNPEP/PLAP. Induced by interferon-gamma, LRAP is able to trim various MHC class I antigenic peptide precursors.
Synonym: FLJ23633,FLJ23701,FLJ23807,L-RAP,LRAP,LRAP.ERAP2
- 分子量
- 106 kDa
- NCBI登录号
- NP_071745
-
