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ENTPD2 Protein (AA 29-460) (His tag)

ENTPD2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7195468
发货至: 中国
  • 抗原 See all ENTPD2 蛋白
    ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 29-460
    宿主
    • 5
    • 5
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    标记
    This ENTPD2 protein is labelled with His tag.
    原理
    Recombinant Human NTPDase 2/ENTPD2 Protein (aa 29-460, His Tag)(Active)
    序列
    Thr 29-Asp460
    产品特性
    A DNA sequence encoding the mature form of human ENTPD2 (Q9Y5L3) (Thr29-Asp460) was expressed, with a polyhistidine tag at the N-terminus.
    纯度
    > 85 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to hydrolyze the 5'phosphate groups from the substrate adenosine 5'triphosphate(ATP).The specific activity is > 5,000 pmoles/min/μg.
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    Discover our top product ENTPD2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))
    别名
    NTPDase 2/ENTPD2 (ENTPD2 产品)
    别名
    MGC76207 Protein, MGC151796 Protein, CD39L1 Protein, NTPDase-2 Protein, Cd39l1 Protein, NTPDase2 Protein, ectonucleoside triphosphate diphosphohydrolase 2 Protein, Ectonucleoside triphosphate diphosphohydrolase 2 Protein, entpd2 Protein, ENTPD2 Protein, enp2 Protein, Entpd2 Protein
    背景

    Background: NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii infection. In L. pneumophila it was demonstrated that an E-NTPDase, similar to CD39, is essential for intracellular bacterial multiplication. NTPDase 2 is an integral membrane protein. In the nervous system, it could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Alternative splicing of NTPDase 2 gene results in multiple transcript variants.

    Synonym: CD39L1;NTPDase-2;RP11-229P13.11-001

    分子量
    49.3 kDa
    UniProt
    Q9Y5L3
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