DUSP14 Protein (His tag,MBP tag)
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- 抗原 See all DUSP14 蛋白
- DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This DUSP14 protein is labelled with His tag,MBP tag.
- 原理
- Recombinant Human DUSP14/MKP-6 Protein (His & MBP Tag)
- 序列
- Met 1 -His 191
- 产品特性
- A DNA sequence encoding the human DUSP14 (O95147) (Met 1 -His 191) was fused with an N-terminal polyhistidine-tagged MBP tag at the N-terminus.
- 纯度
- > 88 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product DUSP14 蛋白
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Dual Specificity Phosphatase 14 (DUSP14) (AA 1-198) protein (GST tag)
DUSP14 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP, PAA
Dual Specificity Phosphatase 14 (DUSP14) (AA 1-198) protein (Strep Tag)Crystallography grade DUSP14 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Dual Specificity Phosphatase 14 (DUSP14) (AA 1-198) protein (Strep Tag)Crystallography grade DUSP14 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Dual Specificity Phosphatase 14 (DUSP14) (AA 1-198), (full length) protein (His-SUMO Tag)DUSP14 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Dual Specificity Phosphatase 14 (DUSP14) protein (Myc-DYKDDDDK Tag)DUSP14 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))
- 别名
- DUSP14/MKP-6 (DUSP14 产品)
- 别名
- MGC84083 Protein, zgc:101746 Protein, DUSP14 Protein, mkp-l Protein, mkp6 Protein, MKP-L Protein, MKP6 Protein, 1110014C10Rik Protein, 2310042C07Rik Protein, D11Ertd395e Protein, Mkp6 Protein, dual specificity phosphatase 14 Protein, dual specificity phosphatase 14 L homeolog Protein, DUSP14 Protein, dusp14.L Protein, dusp14 Protein, Dusp14 Protein
- 背景
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Background: Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosphotyrosine and phosphoserine / phosphothreonine residues in substrates. Unlike many other DUSPs, DUSP14 only contains a catalytic domain within the C-terminal region. In signal transduction, DUSP14 has been considered as negative regulator of the mitogen-activated protein kinase (MAPK) / extracellular signal-regulated kinase 1 / 2 (ERK 1 / 2) pathway. DUSP14 phosphatase activity has been confirmed to be inhibited by PTP inhibitor IV. PTP inhibitor binds to the catalytic site of DUSP14. PTP inhibitor IV effectively and specifically inhibited DUSP14-mediated dephosphorylation of JNK, a member of the mitogen-activated protein kinase (MAPK) family through dephosphorylation of both the Ser / Thr and Tyr residues of MAPKs.
Synonym: MKP-L;MKP6
- 分子量
- 65 kDa
- UniProt
- O95147
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