Doublecortin Protein (DCX) (GST tag)
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- 抗原 See all Doublecortin (DCX) 蛋白
- Doublecortin (DCX)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Doublecortin protein is labelled with GST tag.
- 原理
- Recombinant Human DCX Protein (aa 45-150, GST Tag)
- 序列
- Ala 45-Val 150
- 产品特性
- A DNA sequence encoding the human DCX (O43602-2) N-terminal fragment (Ala 45-Val 150) was fused with the GST tag at the N-terminus.
- 纯度
- > 82 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product DCX 蛋白
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Doublecortin (DCX) (AA 1-360) protein (GST tag)
DCX 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Doublecortin (DCX) (AA 107-208) protein (His-IF2DI Tag)DCX 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Doublecortin (DCX) (AA 1-365) protein (Strep Tag)Crystallography grade DCX 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Doublecortin (DCX) (AA 1-366) protein (Strep Tag)Crystallography grade DCX 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Doublecortin (DCX) (AA 1-361), (full length) protein (His tag)DCX 宿主: 小鸡 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
Doublecortin (DCX) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)DCX 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Doublecortin (DCX) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)DCX 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 1 mM DTT, 10 % glycerol, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Doublecortin (DCX)
- 别名
- DCX (DCX 产品)
- 别名
- DCX Protein, DBCN Protein, DC Protein, LISX Protein, SCLH Protein, XLIS Protein, Dbct Protein, 18C15.5 Protein, doublecortin Protein, DCX Protein, Dcx Protein
- 背景
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Background: DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the adult, it is highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas. DCX is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. It may act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. DCX may in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. It may be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration. Defects in DCX are the cause of lissencephaly X-linked type 1 and subcortical band heterotopia X-linked.
Synonym: DBCN,DC,LISX,SCLH,XLIS
- 分子量
- 39.4 kDa
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