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DLG4 Protein (His tag)

DLG4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318409
发货至: 中国
  • 抗原 See all DLG4 蛋白
    DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 3
    • 3
    资源
    • 6
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This DLG4 protein is labelled with His tag.
    原理
    Recombinant Human DLG4 Protein (His Tag)
    序列
    Met 1-Leu724
    产品特性
    Recombinant Human Postsynaptic Density Protein 95 is produced by our E.coli expression system and the target gene encoding Met1-Leu724 is expressed with a 6His tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DLG4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
    别名
    DLG4 (DLG4 产品)
    别名
    11 Protein, CG1725 Protein, CG1730 Protein, CPD Protein, DLG Protein, DLG-A Protein, Discs-large Protein, Dlg Protein, Dlg-A Protein, Dlg1 Protein, DlgA Protein, Dmel\\CG1725 Protein, Drodlg Protein, PSD95 Protein, SAP97 Protein, anon-EST:Posey93 Protein, anon-WO03040301.258 Protein, anon-WO03040301.260 Protein, anon-WO03040301.268 Protein, d. lg.-1 Protein, dlg Protein, dlg-1 Protein, dlg-A Protein, dlgA Protein, dlgS97 Protein, l(1)10Bf Protein, l(1)G0276 Protein, l(1)G0342 Protein, l(1)G0456 Protein, l(1)G19 Protein, l(1)L11 Protein, l(1)bwn Protein, l(1)d.lg-1 Protein, l(1)d.lg.-1 Protein, l(1)discs large Protein, l(1)dlg Protein, l(1)dlg-1 Protein, l(1)dlg1 Protein, l(1)l.pr.-2 Protein, l(1)lpr-2 Protein, misb Protein, dlgh4 Protein, psd95 Protein, sap90 Protein, sap-90 Protein, LLGL1 Protein, Dlgh4 Protein, PSD-95 Protein, SAP90 Protein, SAP90A Protein, Sap90 Protein, SAP-90 Protein, DLG4 Protein, discs large 1 Protein, discs, large homolog 4 Protein, discs large MAGUK scaffold protein 4 Protein, discs, large homolog 4b (Drosophila) Protein, discs, large homolog 4 (Drosophila) Protein, dlg1 Protein, dlg4 Protein, DLG4 Protein, dlg4b Protein, Dlg4 Protein
    背景

    Background: Disks large homolog 4(DLG4) is a cell membrane protein and it is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains 1 guanylate kinase-like domain,3 PDZ (DHR) domains and 1 SH3 domain. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. DLG4 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin, NMDA receptors, AMPA receptors, and potassium channels.

    Synonym: Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 90, SAP-90, SAP90, PSD95, DLG4

    分子量
    81.9 kDa
    UniProt
    P78352
    途径
    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
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