DPEP1 Protein (His tag)
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- 抗原 See all DPEP1 蛋白
- DPEP1 (Dipeptidase 1 (Renal) (DPEP1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This DPEP1 protein is labelled with His tag.
- 原理
- Recombinant Human Dipeptidase 1/DPEP1 Protein (His Tag)
- 序列
- Asp17-Ser385
- 产品特性
- Recombinant Human Dipeptidase 1 is produced by our Mammalian expression system and the target gene encoding Asp17-Ser385 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product DPEP1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- DPEP1 (Dipeptidase 1 (Renal) (DPEP1))
- 别名
- Dipeptidase 1/DPEP1 (DPEP1 产品)
- 别名
- AI327012 Protein, MBD Protein, MBD1 Protein, MDP Protein, RDP Protein, dipeptidase 1 (renal) Protein, dipeptidase 1 Protein, DPEP1 Protein, Dpep1 Protein
- 背景
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Background: Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem. DPEP1 may play an important role in the regulation of leukotriene activity. DPEP1 expression in cancer is significantly higher than that in normal tissue. However, DPEP1 expression decreased with pathological differentiation, lymph-node and distant metastasis.
Synonym: Dipeptidase 1, Dehydropeptidase-I, Microsomal Dipeptidase, Renal Dipeptidase, hRDP, DPEP1, MDP, RDP, MBD1
- 分子量
- 42.1 kDa
- UniProt
- P16444
- 途径
- Inositol Metabolic Process
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