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CYB5R1 Protein (His tag)

CYB5R1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317282
发货至: 中国
  • 抗原 See all CYB5R1 蛋白
    CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    • 1
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This CYB5R1 protein is labelled with His tag.
    原理
    Recombinant Human CYB5R1 Protein (His Tag)
    序列
    Leu 29-Tyr 305
    产品特性
    A DNA sequence encoding the human CYB5R1 (Q9UHQ9) (Leu 29-Tyr 305) was expressed, with a polyhistidine tag at the N-terminus.
    纯度
    > 97 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CYB5R1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CYB5R1 (Cytochrome B5 Reductase 1 (CYB5R1))
    别名
    CYB5R1 (CYB5R1 产品)
    别名
    B5R.1 Protein, B5R1 Protein, B5R2 Protein, NQO3A2 Protein, humb5R2 Protein, 1500005G05Rik Protein, C80155 Protein, Nqo3a2 Protein, NAD(P)H:quinone oxidoreductase type 3, polypeptide A2 Protein, cytochrome b5 reductase 1 Protein, CYB5R1 Protein, Cyb5r1 Protein
    背景

    Background: Tyrosinase-related protein 1, also known as TYRP1 or TRP1, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations in this enzyme are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. TYRP1 / TRP1 is involved in the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. This enzyme may regulate or influence the type of melanin synthesized. The expression of Tyrosinase-related protein 1 (TYRP1) is regulated by the microphthalmia-associated transcription factor (MITF). There is mounting evidence demonstrating that in addition to its role in eumelanin synthesis, TYRP1 is involved in maintaining stability of tyrosinase proliferation and melanocyte cell death.

    Synonym: B5R.1,B5R1,B5R2,humb5R2,NQO3A2,PRO9865,UNQ3049

    分子量
    33.5 kDa
    UniProt
    Q9UHQ9
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