CST7 Protein (Fc Tag)
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- 抗原 See all CST7 蛋白
- CST7 (Cystatin F (Leukocystatin) (CST7))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CST7 protein is labelled with Fc Tag.
- 原理
- Recombinant Human Cystatin 7/CST7 Protein (Fc Tag)(Active)
- 序列
- Met 1-His 145
- 产品特性
- A DNA sequence encoding the human Cystatin F precursor (NP_003641.3) (Met 1-His 145) was expressed with the fused Fc region of human IgG1 at the C-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC (R&D Systems, Catalog#ES008). The IC50 value is <5 nM.
- Top Product
- Discover our top product CST7 蛋白
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Cystatin F (Leukocystatin) (CST7) (AA 1-167) protein (GST tag)
CST7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cystatin F (Leukocystatin) (CST7) (AA 68-167) protein (GST tag)CST7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Cystatin F (Leukocystatin) (CST7) protein (His tag)CST7 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Cystatin F (Leukocystatin) (CST7) (Active) protein (Fc Tag)CST7 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 93 % as determined by SDS-PAGE Active
Cystatin F (Leukocystatin) (CST7) (AA 20-145) protein (His tag)Crystallography grade CST7 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Cystatin F (Leukocystatin) (CST7) (AA 19-144) protein (His tag)Crystallography grade CST7 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CST7 (Cystatin F (Leukocystatin) (CST7))
- 别名
- Cystatin 7/CST7 (CST7 产品)
- 别名
- CST7 Protein, LOC100232568 Protein, cytf Protein, CMAP Protein, Cmap Protein, cystatin F Protein, Cystatin F Protein, cystatin F (leukocystatin) Protein, CST7 Protein, cytf Protein, Cst7 Protein
- 背景
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Background: The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain types of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new diagnosis and prevention approach of certain human carcinomas metastasis.
Synonym: Cystatin-F, Cystatin-7, Cystatin-Like Metastasis-Associated Protein, CMAP, Leukocystatin, CST7
- 分子量
- 41.3 kDa
- NCBI登录号
- NP_003641
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